The relationship between psychological distress and traditional clinical variables: a 2 year prospective study of 216 patients with early rheumatoid arthritis

British Journal of Rheumatology
L M SmedstadT K Kvien

Abstract

In this longitudinal study (12 and 24 months follow-up) of 216 patients with early rheumatoid arthritis (RA) (< or = 4 yr duration), we assessed the strength and stability of the relationship between psychological distress and traditional clinical variables examined the ability of these clinical variables to predict changes in mental distress, and explored the directionality between mental distress and the other clinical variables. Study variables were symptoms of anxiety and depression measured by the Arthritis Impact Measurement Scales, tender joint counts, erythrocyte sedimentation rate (ESR), and self-reported pain and disability. Psychological distress showed high levels of stability over time. Pain and disability were the two variables most strongly and consistently related to mental distress. High levels of disability predicted an increase in depression during the next year; otherwise, changes in psychological distress were not predicted by disease-related variables. Attempts at causal modelling of the temporal relationship between mental distress, pain and disability failed to yield consistent results.

Citations

Dec 13, 2005·Rheumatology International·T N HyphantisA A Drosos
Mar 3, 2007·Clinical Rheumatology·Eva PalkonyaiEszter Meszaros
Oct 20, 2005·Scandinavian Journal of Rheumatology·T K Kvien, T Uhlig
Oct 27, 2009·Disability and Rehabilitation·Emma S SjöquistChristina H Opava
Jun 15, 2011·Journal of Psychosomatic Research·Karl LooperUNKNOWN McGill Early Arthritis Research Group
Oct 21, 2009·Comprehensive Psychiatry·Susana Vázquez-RiveraJosé Luis Carrasco
Oct 31, 2009·Arthritis and Rheumatism·M MargarettenL Julian
Oct 3, 2006·Arthritis and Rheumatism·Mathilde M H StratingWijbrandt H van Schuur
Feb 2, 2008·Arthritis and Rheumatism·Betsy SleathAshley Beard
Jan 3, 2013·Arthritis Care & Research·Patricia L DobkinGilles Boire
May 3, 2006·Journal of Psychosomatic Research·Tanya CovicGraydon Howe
Nov 21, 2000·Rheumatic Diseases Clinics of North America·M HerrmannR H Straub
Mar 15, 2011·Pain·Stephen T WegenerUNKNOWN LEAP Study Group
Dec 3, 2016·Arthritis Research & Therapy·Jenny HumphreysDeborah Symmons
May 26, 2004·PharmacoEconomics·Tore K Kvien
May 10, 2018·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Yosuke HattoriAtsushi Kaneko
Jan 17, 2007·Clinical Orthopaedics and Related Research·Murray Baron, Russell Steele
Dec 17, 2015·Clinical Practice and Epidemiology in Mental Health : CP & EMH·Benjamin J R StewartJane M Andrews
Oct 9, 2018·Arthritis Care & Research·Yukako NakagamiTsuneyo Mimori

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.