The relationship between resting heart rate and peak VO2: A comparison of atrial fibrillation and sinus rhythm

European Journal of Preventive Cardiology
Yuko KatoTakeshi Yamashita

Abstract

Resting heart rate is a surrogate marker associated with achieved exercise capacity, which has been observed in patients with sinus rhythm. The aim of this study was to examine and compare the relationships between resting heart rate and peak oxygen consumption in atrial fibrillation and sinus rhythm. A total of 2160 consecutive patients undergoing cardiopulmonary exercise testing in our single-hospital cohort were divided into two groups according to rhythm status: an atrial fibrillation group (N = 320) and a sinus rhythm group (N = 1840). In the total cohort and sinus rhythm group, resting heart rate was negatively correlated with percentage of predicted peak oxygen consumption (Ptrend < 0.0001); in atrial fibrillation patients, this correlation was apparently positive (Ptrend = 0.032). Multivariate analysis of the total cohort showed a significant interaction between resting heart rate and rhythm status for peak oxygen consumption after adjustments for age, sex, ejection fraction, structural heart diseases and heart rate-lowering drugs. In the sinus rhythm group, resting heart rate was an independent, negative contributing factor for peak oxygen consumption, even after the adjustments for patient background. However, in the ...Continue Reading

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Citations

May 10, 2017·European Journal of Preventive Cardiology·Wesley T O'NealElsayed Z Soliman
Jul 20, 2018·European Journal of Preventive Cardiology·Paolo E Puddu
Aug 31, 2018·European Journal of Preventive Cardiology·Kazufumi AiharaTakeshi Yamashita
Sep 6, 2018·European Journal of Preventive Cardiology·Claudio Passino, Michele Emdin
Oct 16, 2018·European Journal of Preventive Cardiology·Massimo F Piepoli
Dec 19, 2018·European Journal of Heart Failure·Markus S AnkerStefan D Anker
Mar 1, 2018·European Journal of Preventive Cardiology·Jari A LaukkanenSetor K Kunutsor

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