The relationship between serum uric acid and lipid profile in Bangladeshi adults
Abstract
Although the link between elevated uric acid and metabolic syndrome has been reported in some studies; the relationship of serum uric acid (SUA) with lipid profile has not well studied or little is known so far. This study was conducted to assess the relationship between SUA and lipid profile among the general adults in Bangladesh. In total, 280 blood samples were collected from general adult participants (male, n = 150 and female, n = 130) and analyzed for serum lipid profile (TC, TG, HDL and LDL) and SUA levels. The study subjects were divided by quartiles based on SUA levels (Q1: ≤225 μmol/L, Q2: 226-285 μmol/L, Q3: 286-340 μmol/L and Q4: > 340 μmol/L). Linear regression modeling was used to evaluate the relationship between SUA and lipid levels. The prevalence of hyperuricemia was 9.2% in males and 10.4% in females. The mean level of SUA was significantly higher in male (317 ± 90 μmol/L) than in the female (255 ± 65 μmol/L) subjects (p < 0.001). An increasing trend for elevated lipid profile was observed in both gender with increasing levels of SUA in the quartiles (p < 0.05). In regression analysis, a significant positive correlation was found between SUA and TG, TC and LDL (p < 0.01) while an inverse correlation was obser...Continue Reading
References
Serum uric acid and risk of coronary heart disease: Atherosclerosis Risk in Communities (ARIC) Study
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