The Relationship between Serum Vitamin C and Uric Acid Levels, Antioxidant Status and Coronary Artery Disease: a Case-Control Study

Clinical Nutrition Research
Aida TorkzabanMehrdad Namdari

Abstract

Coronary artery disease (CAD) is among the main causes of death in adults. Increase of oxidative stress and defects in antioxidant defense play a major role in endothelium performance and are affecting factors in the progress of atherosclerosis. The aim of this study was to measure serum levels of uric acid (UA) and vitamin C as well as the antioxidant status in patients with CAD, and compared them with those in healthy individuals. The present case-control study was performed on 44 cases and 44 controls. Demographic data and anthropometric indices were measured. The Food Frequency Questionnaire (FFQ) and International Physical Activity Questionnaire (IPAQ) were completed. After 12 hours of fasting,10 mL blood was sampled from the participants. Serum levels of UA, vitamin C, Total Antioxidant Capacity (TAC) and Malondialdehyde (MDA) were also measured. The data were finally analyzed by SPSS v22. A significant difference was observed between the groups in terms of UA and vitamin C. However, mean levels of MDA and TAC were not significantly different between groups. The differences between groups in terms of vitamin A, vitamin E, beta-carotene, zinc and selenium intakes were not significant either. A significant difference was de...Continue Reading

References

Jan 1, 1994·Physiological Reviews·B P Yu
Jan 7, 1999·Clinica Chimica Acta; International Journal of Clinical Chemistry·R DelportW J Vermaak
Jul 3, 1999·Annals of Internal Medicine·B F CulletonD Levy
Dec 22, 1999·Proceedings of the Society for Experimental Biology and Medicine·L L Ji
Dec 21, 2000·Current Atherosclerosis Reports·M MaytinJ Loscalzo
Jun 9, 2001·The American Journal of Cardiology·K R TuttleR J Johnson
Jan 22, 2002·The Journal of Cardiovascular Nursing·Sue PenckoferKristine Florczak
Apr 16, 2002·Current Opinion in Pharmacology·Michael H Alderman
Aug 2, 2003·American Heart Journal·Brett E FensterStanley G Rockson
Mar 18, 2004·Current Medical Research and Opinion·Michael Alderman, Kala J V Aiyer
Sep 24, 2004·Physiological Reviews·Roland Stocker, John F Keaney
Oct 21, 2004·Therapeutische Umschau. Revue thérapeutique·M Alderman, J S Redfern
Jul 26, 2005·Circulation Journal : Official Journal of the Japanese Circulation Society·Tae Woo YooDong Geuk Keum
Aug 9, 2005·The American Journal of Medicine·Joshua F BakerH Ralph Schumacher
Apr 6, 2007·The Tohoku Journal of Experimental Medicine·Zorana Jelić-IvanovićSlavica Spasić
Mar 11, 2009·Archives of Internal Medicine·Hyon K ChoiGary Curhan
Mar 3, 2010·The Korean Journal of Internal Medicine·Hong Euy LimChang Gyu Park
Nov 3, 2012·International Journal of Hypertension·Maguy ChihaEdgar G Chedrawy
May 11, 2013·Journal of Biosciences·A Supriya SimonT Vijayakumar
Aug 7, 2013·BMC Cardiovascular Disorders·James KayimaFred Nuwaha
Aug 9, 2016·Annals of Translational Medicine·Fabian Sanchis-GomarAlejandro Lucia
Jun 15, 2017·The American Journal of Cardiology·Maria DanielPer Tornvall

❮ Previous
Next ❯

Citations

Aug 7, 2021·Phytotherapy Research : PTR·Saeideh SabbaghzadeganMajid Dadmehr

❮ Previous
Next ❯

Methods Mentioned

BETA
MDA

Software Mentioned

SPSS
Excel
N4

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.