The relationship between structure and function as measured by OCT and Octopus perimetry

The British Journal of Ophthalmology
Blanca MonsalveMichele Iester

Abstract

To determine the structure-function relationship between equivalent visual field areas obtained with the Octopus perimeter (OP), and the peripapillary retinal nerve fibre layer (RNFL) thickness measured with spectral-domain optical coherence tomography (OCT) in healthy individuals and patients with glaucomatous optic neuropathy. Eighty-eight normal subjects and 150 patients with open-angle glaucoma were prospectively recruited. Eligible participants for the glaucoma group were required to have elevated intraocular pressure and glaucomatous optic nerve head morphology. All participants underwent reliable automated perimetry with OP, and optic nerve head imaging with the Cirrus OCT. Principal component analysis of the mean threshold values for the visual field test points were performed independently for each hemifield. Pearson correlations were calculated between visual field regions and RNFL thickness sectors. Mild to moderate correlations were observed between the visual field regions and the peripapillary RNFL thicknesses. Each visual field region was significantly correlated with more than one RNFL sector, and vice versa. The strongest correlation was observed between the RNFL thickness at 5 and 7 clock-hour positions and th...Continue Reading

References

Apr 15, 1991·American Journal of Ophthalmology·A Tuulonen, P J Airaksinen
May 1, 1991·International Ophthalmology·J Weber, H Ulrich
Feb 1, 1969·The British Journal of Ophthalmology·A J Lyne, C I Phillips
Aug 1, 1997·Acta Ophthalmologica Scandinavica·B BengtssonH Rootzén
Jan 27, 2000·Ophthalmology·J MoralesM González de la Rosa
Apr 27, 2000·The British Journal of Ophthalmology·M IesterW M Budde
Jun 15, 2000·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·A G JünemannJ Jonas
Oct 3, 2000·Ophthalmology·D F Garway-HeathR A Hitchings
Dec 24, 2003·Investigative Ophthalmology & Visual Science·Michael WallCaridad F Brito
May 27, 2004·Investigative Ophthalmology & Visual Science·Patricio G SchlottmannDavid F Garway-Heath
Sep 28, 2005·Investigative Ophthalmology & Visual Science·Stuart K GardinerGeorge A Cioffi
Jul 26, 2006·Journal of Glaucoma·Christian Y MardinBerthold Lausen
Sep 5, 2006·Ophthalmology·Neha N ShahLinda M Zangwill
Apr 2, 2008·Investigative Ophthalmology & Visual Science·Antonio FerrerasJulián García-Feijoo
Mar 28, 2009·Investigative Ophthalmology & Visual Science·Andrew TurpinAllison M McKendrick
Jun 6, 2009·The British Journal of Ophthalmology·M Gonzalez-HernandezM Gonzalez de la Rosa
Oct 16, 2010·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Barbara Cvenkel, Alenka Sket Kontestabile
Feb 22, 2012·Clinical & Experimental Ophthalmology·Rizwan MalikDavid F Garway-Heath

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Investigative Ophthalmology & Visual Science
Antonio FerrerasJulián García-Feijoo
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
Isabel Fuertes-LazaroLuís E Pablo
Investigative Ophthalmology & Visual Science
Blanca FerrandezMichele Iester
© 2021 Meta ULC. All rights reserved