The relationship between subthreshold and suprathreshold ocular dominance in cat primary visual cortex.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Nicholas J Priebe

Abstract

Primary visual cortex (V1) is the site at which right and left eye pathways are first integrated, leading to a representation of the visual world in depth. The ocular dominance (OD) of individual cortical neurons varies and may be changed by altering visual experience during the developmental critical period. Estimates of OD, commonly used to quantify the right and left eye synaptic inputs, have previously been based on spike rate. Membrane potential (V(m)), however, is more closely related to the synaptic inputs onto neurons and should therefore more closely reflect the degree of input from the two eyes. To determine the relationship between OD based on membrane potential and on spike rate, intracellular recordings were made from visual cortical neurons. OD based on spike rate was systematically more monocular than OD based on membrane potential. The discrepancy between membrane-potential OD and spike-rate OD may be accounted for by a simple model of V(m)-to-spike-rate transformation.

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Citations

Jun 28, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Benjamin SchollNicholas J Priebe
Oct 16, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Joshua X GittelmanGeorge D Pollak
Aug 10, 2011·Neural Plasticity·J Alexander HeimelChristiaan N Levelt
Sep 4, 2015·The Journal of Physiology·Benjamin SchollNicholas J Priebe
Jul 31, 2012·Neuron·Nicholas J Priebe, David Ferster
Jan 15, 2014·PLoS Computational Biology·Sean T KellyGarrett B Stanley
Sep 7, 2013·PLoS Computational Biology·Mengchen Zhu, Christopher J Rozell
Jun 28, 2018·Journal of Neurophysiology·Iris Reuveni, Edi Barkai
Mar 22, 2013·Journal of Neurophysiology·Benjamin SchollNicholas J Priebe
Sep 15, 2017·PloS One·Trevor C GriffenArianna Maffei
May 24, 2017·Annual Review of Vision Science·Nicholas J Priebe

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