The relationship between the cornea and the optic disc

Eye
J M KimS W Cho

Abstract

To evaluate the structural relationship between the cornea and the optic disc in normal subjects. This hospital-based observational study included 205 eyes from 205 individuals who were diagnosed as normal at our glaucoma clinic. The subjects underwent an eye examination, optic disc imaging with optic disc photography, optical coherence tomography, IOL master, specular microscopy, and ultrasound corneal pachymetry. In univariate regression models (Pearson's correlation coefficient), the cup-to-disc (CD) ratio showed a negative correlation with corneal curvature (r=-0.315, P<0.001) and central corneal thickness (r=-0.206, P=0.005), and a positive correlation with white-to-white diameter (horizontal limbus to limbus distance, r=0.215, P=0.003). In multiple linear regression models with CD ratio as the dependant parameter, the CD ratio was still significantly associated with corneal curvature (β=-0.205, P=0.011) and white-to-white diameter (β=0.207, P=0.010). The central corneal thickness failed to show statistical significance, but did show a negative correlation with borderline significance (β=-0.133, P=0.075). Eyes with a large CD ratio have large and flat corneas; this may suggest that there is a structural relationship betwee...Continue Reading

References

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Citations

May 15, 2013·Cornea·Caroline A BlackieDonald R Korb
Jul 18, 2014·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Gauti JóhannessonPer Hallberg
Jan 29, 2013·American Journal of Ophthalmology·Joon Mo KimJoseph Caprioli
Jun 2, 2016·Current Eye Research·Seong Hee ShimUNKNOWN Korean Ophthalmological Society
Oct 13, 2015·Korean Journal of Ophthalmology : KJO·Yang Jae KimUNKNOWN Epidemiologic Survey Committee of the Korean Ophthalmological Society
Sep 16, 2014·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Anila BakullariErnest Moy
Dec 30, 2014·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Hyo Jung GyeKi Ho Park
Nov 6, 2020·Investigative Ophthalmology & Visual Science·Diane N SayahMark R Lesk

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