The relationship between the follicular variant of papillary thyroid cancer and follicular adenomas

Surgery
Raman MehrzadPer-Olof Hasselgren

Abstract

Reports suggest that the incidence of tumors diagnosed as follicular variant of papillary thyroid cancer (FVPTC) is increasing and that this increase may reflect changes in diagnostic criteria with tumors presently being diagnosed as FVPTC previously being defined as follicular lesions, in particular follicular adenomas. Changes during recent years in the relationship between the incidence of FVPTC and follicular adenomas have not been reported. Herein, we have compared changes in the incidence of FVPTC with changes in the incidence of follicular adenomas. The study is a retrospective analysis of a prospective database of patients undergoing thyroid surgery between January 1, 2004, and December 31, 2013. A total of 953 thyroid procedures performed in 851 patients were reviewed. The incidence of FVPTC increased approximately 4-fold during the study period when expressed as percentage of all thyroidectomies with the increase mainly reflecting an increase in the incidence of noninvasive FVPTC. The incidence of follicular adenomas decreased in a reverse fashion resulting in a >10-fold increase in the ratio between FVPTC and follicular adenomas during the study period. Although the present results suggest that some tumors previously...Continue Reading

References

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Citations

Nov 4, 2016·Endocrine-related Cancer·Pedro Weslley RosarioMaria Regina Calsolari
Mar 7, 2017·Diagnostic Cytopathology·Marc Pusztaszeri, Manon Auger
Dec 12, 2018·Pathology International·Kennichi KakudoChan Kwon Jung

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