PMID: 9192227Jun 1, 1997Paper

The relationship between weight and response to cholesterol-lowering diets in women

International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity
J S HannahB V Howard

Abstract

To determine whether factors related to body weight might influence the cholesterol lowering response to diet. Run-In diet followed by crossover to low fat diets; average response is reported. Sixty-three subjects (30 men and 33 women) with moderately elevated plasma cholesterol levels. Lipid and anthropometric measurements. Data were analyzed as a repeated measures analysis of variance with lipid lowering response in all combined cholesterol lowering diets compared to baseline. LDL cholesterol lowering was significantly affected by BMI in women (P = 0.01) but not in men (P = 0.54). There was also a weak effect of waist-hip (W/H) ratio on response (P = 0.127) in women, with the lower responders having a higher W/H ratio but there was no effect of W/H ratio in men (P = 0.86). These results suggest that overweight women with elevated plasma cholesterol may be less responsive to reducing their cholesterol levels with diet.

Citations

Nov 1, 2005·Current Atherosclerosis Reports·Martijn B Katan
Sep 8, 2010·Current Atherosclerosis Reports·Emilio RosJoan Sabaté
Jul 1, 2010·Nutrients·Emilio Ros
Feb 15, 2012·Advances in Nutrition·Michael R FlockPenny M Kris-Etherton
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