PMID: 7108447May 1, 1982

The relationship of HDL-apolipoprotein A-I and HDL-Cholesterol to risk factors of coronary heart disease: initial results of the prospective epidemiological study in company employees in Westfalia

Journal of Clinical Chemistry and Clinical Biochemistry. Zeitschrift Für Klinische Chemie Und Klinische Biochemie
G AssmannH Schriewer


In a prospective epidemiologic study in company employees in Westfalia aimed at improving early diagnosis of coronary heart disease in 3069 men and 1387 women, concentrations of HDL-apolipoprotein A-I and HDL-cholesterol were measured and the results were correlated with several risk factors of coronary heart disease. A negative correlation between hypertriglyceridaemia and HDL-cholesterol (r = 0.25 male;-0.27 female;p less than 0.001) and between relative body weight and HDL-cholesterol (r=-0.21 male;-0.20 female;p less than 0.001) could be shown but not between hypertriglyceridaemia and HDL-apolipoprotein A-I and between relative body weight and HDL-apolipoprotein A-I. In cigarette smokers HDL-apolipoprotein A-I as well as HDL-cholesterol were found to be lower than in non-smokers. On the other hand HDL-apolipoprotein A-I but not HDL-cholesterol was positively correlated with systolic and diastolic blood pressure.


Jun 1, 1978·European Journal of Clinical Investigation·T IshikawaN E Miller
Feb 5, 1976·The New England Journal of Medicine·G G RhoadsA Kagan

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Apolipoproteins A
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