The relationship of optic disk cupping to retinal vein occlusion: the Beaver Dam Eye Study
Abstract
To examine the association between optic disk cupping and retinal vein occlusion (RVO). Prospective epidemiologic study. setting: Population-based prospective study in Beaver Dam, Wisconsin. study population: Adults aged 43 to 86 years at baseline (n = 4926). observation procedures: Optic disk cupping and RVO were determined from retinal photographs. A standardized medical examination and questionnaire were administered. main outcome measure: Ten-year cumulative incidence of RVO. There were 58 persons who developed incident RVO at 5 (n = 31) or 10 (n = 27) years after the baseline examination. Those sustaining RVO were older, had higher intraocular pressure (IOP), and were more likely to have definite or probable glaucoma at the baseline examination. The odds of having an incident RVO increased with increasing cup-to-disk ratio at baseline (odds ratio [OR] = 1.29/0.1 increase in cup-to-disk ratio, 95% confidence interval 1.07, 1.56), while controlling for age, systolic blood pressure, current smoking, diabetes status, and IOP. A similar OR was found after excluding those with glaucoma. Excluding persons with central (as opposed to branch) vein occlusion did not have a significant effect on the OR. Cup-to-disk ratio is a signifi...Continue Reading
References
Cup-to-disc ratio, intraocular pressure, and primary open-angle glaucoma in retinal venous occlusion
Citations
Optic disk analysis with heidelberg retina tomography in patients with branch retinal vein occlusion
Mystery of Retinal Vein Occlusion: Vasoactivity of the Vein and Possible Involvement of Endothelin-1
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