The relationship of optic disk cupping to retinal vein occlusion: the Beaver Dam Eye Study

American Journal of Ophthalmology
Barbara E K KleinRonald Klein

Abstract

To examine the association between optic disk cupping and retinal vein occlusion (RVO). Prospective epidemiologic study. setting: Population-based prospective study in Beaver Dam, Wisconsin. study population: Adults aged 43 to 86 years at baseline (n = 4926). observation procedures: Optic disk cupping and RVO were determined from retinal photographs. A standardized medical examination and questionnaire were administered. main outcome measure: Ten-year cumulative incidence of RVO. There were 58 persons who developed incident RVO at 5 (n = 31) or 10 (n = 27) years after the baseline examination. Those sustaining RVO were older, had higher intraocular pressure (IOP), and were more likely to have definite or probable glaucoma at the baseline examination. The odds of having an incident RVO increased with increasing cup-to-disk ratio at baseline (odds ratio [OR] = 1.29/0.1 increase in cup-to-disk ratio, 95% confidence interval 1.07, 1.56), while controlling for age, systolic blood pressure, current smoking, diabetes status, and IOP. A similar OR was found after excluding those with glaucoma. Excluding persons with central (as opposed to branch) vein occlusion did not have a significant effect on the OR. Cup-to-disk ratio is a signifi...Continue Reading

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Citations

Aug 7, 2010·Clinical Ophthalmology·Niral Karia
Jan 14, 2011·Journal of the Neurological Sciences·S B SycP A Calabresi
Dec 25, 2009·Ophthalmology·Edward M BarnettUNKNOWN Ocular Hypertension Treatment Study Group
Apr 22, 2015·Journal of Thrombosis and Haemostasis : JTH·K A PontoA Mirshahi
Oct 30, 2016·American Journal of Ophthalmology·Hae-Young Lopilly ParkChan Kee Park
Jun 13, 2017·The Open Ophthalmology Journal·Elisabeth Wittström
Jul 4, 2019·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Orhan AltunelSüleyman Demircan
Dec 8, 2007·Korean Journal of Ophthalmology : KJO·Young Cheol Yoo, Ki Ho Park
May 11, 2018·F1000Research·Daniel D Esmaili, David S Boyer
Dec 15, 2020·Lancet·Ingrid U ScottValérie Biousse
Nov 30, 2019·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Ender Sirakaya, Bekir Kucuk
Dec 1, 2021·Acta Ophthalmologica·Aditya V BelamkarAmir R Hajrasouliha

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