PMID: 6405665May 1, 1983Paper

The relationship of phenotype changes in Pseudomonas aeruginosa to the clinical condition of patients with cystic fibrosis

The American Review of Respiratory Disease
A R PenkethJ C Batten

Abstract

Strains of Pseudomonas aeruginosa, isolated from the sputum of relatively fit patients with cystic fibrosis (CF) who had been recently colonized by the organism, showed typical cultural and serologic characteristics. The majority of strains of P. aeruginosa isolated from CF patients with chronic bronchopulmonary infection had 3 distinctive features, loss of 0 serotype reaction, expression of a new somatic antigen, and sensitivity to normal human serum. Patients with organisms with one or two of these features were more severely affected by the disease. The appearance of these variants may represent a critical stage in the progression of CF.

Citations

Jul 1, 1989·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·B OjeniyiV T Rosdahl
Feb 1, 1987·Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. Section B, Microbiology·B OjeniyiN Høiby
Nov 21, 2001·Pharmacotherapy·R L White
Jul 28, 2018·The Journal of Antimicrobial Chemotherapy·Mar RederoAna I Prieto
Feb 1, 1986·Journal of Clinical Pathology·K FonsecaT L Pitt
Nov 26, 2009·PloS One·Jean-Paul PirnayDaniel De Vos
Oct 31, 2017·Chronic Respiratory Disease·Christiaan Dm WijersBenjamin M Gaston
Nov 28, 2017·Scientific Reports·Tomasz OlszakZuzanna Drulis-Kawa
Jun 3, 1985·Klinische Wochenschrift·U WinklerK E Jäger
Nov 12, 2002·Proceedings of the National Academy of Sciences of the United States of America·Laura Silo-SuhDennis E Ohman
May 26, 1999·American Journal of Respiratory Cell and Molecular Biology·P S ThorneM A O'Neill
Apr 1, 1988·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·T C Montie, T R Anderson
Jan 1, 1997·The Pediatric Infectious Disease Journal·A Smith
Jan 1, 1990·Pediatric Pulmonology·M S Zach
Jul 1, 1997·FEMS Immunology and Medical Microbiology·E S StanislavskyC Lugowski
May 1, 1994·FEMS Immunology and Medical Microbiology·S L ButlerJ R Govan
Sep 8, 1999·Microbiology and Molecular Biology Reviews : MMBR·H L RocchettaJ S Lam
Jul 1, 1984·Journal of Clinical Microbiology·J A FyfeJ R Govan
Jun 1, 1990·Journal of Clinical Microbiology·M FeganJ A Fuerst
Jun 1, 1991·Journal of Clinical Microbiology·B TümmlerH von der Hardt
Sep 15, 2004·Journal of Clinical Microbiology·Arlene D Vinion-DubielJoanna B Goldberg
Jan 1, 1991·Clinical Microbiology Reviews·P H Gilligan

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