PMID: 7334410Dec 1, 1981Paper

The relationship of plasma levels of pyridostigmine to clinical effect in patients with myasthenia gravis

Journal of Neurology, Neurosurgery, and Psychiatry
S C DavisonK Chan

Abstract

The relationship between plasma levels of pyridostigmine to clinical evaluation of muscle power was examined in nine patients with myasthenia gravis during treatment with pyridostigmine in doses of 60 to 1040 mg daily. Five of the nine subjects demonstrated a trend towards a positive correlation, but in only two of them was this statistically significant at p < 0.05. In addition, the presence or absence of a possible correlation between muscle power and plasma concentration was not related to the duration of the disease, additional prednisolone therapy or thymectomy.

References

Jan 1, 1976·Annals of the New York Academy of Sciences·D Grob, T Namba
Nov 1, 1977·Clinical Pharmacology and Therapeutics·K Chan, T N Calvey
Jan 1, 1976·Annals of the New York Academy of Sciences·W K Engel
Feb 1, 1977·Clinical Pharmacology and Therapeutics·T N Calvey, K Chan
Jun 1, 1976·Neurology·S L CohanD S O'Doherty
Mar 1, 1980·British Journal of Clinical Pharmacology·S C DavisonK Chan
Jun 1, 1959·GP·K R MAGEE

❮ Previous
Next ❯

Citations

Oct 1, 1991·European Journal of Drug Metabolism and Pharmacokinetics·C Tharasse-BlochP Gajdos
Jul 16, 2008·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Adil E BharuchaAlan R Zinsmeister
Oct 1, 1983·Journal of Neurology, Neurosurgery, and Psychiatry·S M AquiloniusE Stålberg
Sep 1, 1985·Journal of Clinical and Hospital Pharmacy·K Chan
Aug 1, 1996·Journal of Pharmacokinetics and Biopharmaceutics·K YamamotoT Iga
Jun 1, 1990·Journal of Neurology, Neurosurgery, and Psychiatry·U Breyer-PfaffF Schumm
Feb 1, 1986·Annals of Neurology·J M DooleyB S Brown

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved