The relationship of waist circumference and body mass index to grey matter volume in community dwelling adults with mild obesity

Obesity Science & Practice
Y K HayakawaK Ohtomo

Abstract

Previous work has shown that high body mass index (BMI) is associated with low grey matter volume. However, evidence on the relationship between waist circumference (WC) and brain volume is relatively scarce. Moreover, the influence of mild obesity (as indexed by WC and BMI) on brain volume remains unclear. This study explored the relationships between WC and BMI and grey matter volume in a large sample of Japanese adults. The participants were 792 community-dwelling adults (523 men and 269 women). Brain magnetic resonance images were collected, and the correlation between WC or BMI and global grey matter volume were analysed. The relationships between WC or BMI and regional grey matter volume were also investigated using voxel-based morphometry. Global grey matter volume was not correlated with WC or BMI. Voxel-based morphometry analysis revealed significant negative correlations between both WC and BMI and regional grey matter volume. The areas correlated with each index were more widespread in men than in women. In women, the total area of the regions significantly correlated with WC was slightly greater than that of the regions significantly correlated with BMI. Results show that both WC and BMI were inversely related to re...Continue Reading

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Citations

Aug 21, 2019·Frontiers in Aging Neuroscience·Frauke BeyerA Veronica Witte
Dec 5, 2019·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Thang M LeChiang-Shan R Li
Sep 16, 2020·Multiple Sclerosis and Related Disorders·Rachel GaliotoStephen M Rao
Jul 31, 2021·Journal of Obesity·Erick Gómez-ApoJuan Silva-Pereyra
Jul 21, 2021·Journal of the American College of Nutrition·Nezire İnceHalit Tanju Besler
Aug 28, 2021·Brain Sciences·Marina Fernández-AndújarNatalia García-Casares

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Software Mentioned

spm
Statistical Parametric Mapping
matlab
VBM8
Windows

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