The release of histamine from human basophils by radiological contrast agents

The British Journal of Radiology
E S AssemP Dawson

Abstract

The capacity of conventional and new low-osmolality contrast agents to stimulate histamine release from human basophils has been studied in vitro. When compared on an iodine concentration basis, the new agents release less histamine than the conventional agents at intermediate and higher concentration. However, the newer compounds exhibit a biphasic histamine release response to increasing iodine concentration with a low concentration peak, a phenomenon not previously described. Among the conventional ionic agents, meglumine salts were confirmed to be more potent histamine releasers than sodium salts. Possible mechanisms of this histamine release and the bearing of the findings on the safety of contrast media are discussed.

References

Oct 1, 1979·The Journal of Allergy and Clinical Immunology·F C CogenB Zweiman
Jul 1, 1977·Radiology·M R LittnerC E Putman
Jul 1, 1976·Investigative Radiology·J H LangW P Kolb
Jan 1, 1971·International Archives of Allergy and Applied Immunology·E S Assem, H O Schild
Sep 1, 1971·Radiology·E C LasserJ Lang
Aug 1, 1974·Agents and Actions·G SeidelC Meyer-Burgdorff
Nov 1, 1970·Investigative Radiology·G Ansell
Jun 1, 1981·The Journal of Clinical Investigation·S R FindlayL M Lichtenstein
Apr 1, 1981·Anaesthesia·E S AssemR D Levis
Mar 1, 1983·Clinical Radiology·P DawsonJ Britton
Sep 1, 1983·The British Journal of Radiology·P Dawson, D Edgerton
Nov 1, 1980·Investigative Radiology·C M Arroyave
May 1, 1980·Investigative Radiology·P P HarnishA N King

❮ Previous
Next ❯

Citations

Apr 16, 1998·The British Journal of Radiology·P T Peachell, S K Morcos
Mar 20, 1998·The British Journal of Radiology·Y X WangS K Morcos
Apr 1, 1988·The British Journal of Radiology·L BesterA Scher
May 24, 2003·The British Journal of Radiology·S K Morcos
Oct 1, 1984·British Heart Journal·R Hayward, P Dawson
Jun 1, 2000·Clinical Reviews in Allergy & Immunology·P L Lieberman, R L Seigle
Sep 1, 1984·Clinical Radiology·A R ManhireR Dennet
Jan 14, 2005·Allergy·K BrockowUNKNOWN EAACI interest group on drug hypersensitivity
Jan 22, 2005·Annales Françaises D'anesthèsie Et De Rèanimation·P DewachterC Mouton-Faivre
Mar 1, 1991·Current Problems in Diagnostic Radiology·H O Stolberg, B L McClennan
Sep 5, 1989·The American Journal of Cardiology·P Dawson
Nov 15, 1990·The American Journal of Cardiology·J L VacekG D Beauchamp
Feb 6, 1999·European Journal of Radiology·S K MorcosJ O Karlsson
Jan 1, 1984·Acta Radiologica: Diagnosis·P DawsonC Hill
Apr 13, 2004·Journal of the American Veterinary Medical Association·Cornelia I GunkelEric A Ferrell
Jul 17, 2008·Journal of the American Veterinary Medical Association·Rachel E Pollard, Peter J Pascoe
Apr 1, 1991·Catheterization and Cardiovascular Diagnosis·W H Matthai, J W Hirshfeld
Jun 1, 1994·The Journal of Urology·J J Keizur, S Das
Feb 1, 1994·The Annals of Pharmacotherapy·E T Wittbrodt, S A Spinler
Jan 1, 1995·Acta Radiologica. Supplementum·N D PughJ O Karlsson

❮ Previous
Next ❯

Related Concepts

Related Feeds

Basophils

Basophils are myeloid cells with a high affinity IgE receptor and is involved in inflammatory responses during allergy. Discover the latest research on Basophils here.