The relevance of vitamin D in the oral health of HIV infected patients.

The Journal of Steroid Biochemistry and Molecular Biology
Chrispinus Hakimu MumenaMohammed S Razzaque

Abstract

HIV infection affects 36.9 million people globally, and vitamin D deficiency is a global public health concern for HIV patients. Approximately 70 %-80 % of HIV-infected patients have vitamin D deficiency. The deficiency is associated with many pathologies such as immune disorders, infectious diseases, chronic inflammation, oral diseases, as well as the fast progression of HIV. The causes of vitamin D deficiency in HIV infections include HIV itself, traditional factors such as less sun exposure, mal-absorption, hypercholesterolemia, seasonal variation, poor nutrition as well as some HAART drugs like efavirenz. Vitamin D has an immunomodulatory, anti-inflammatory, and anti-proliferative function. In the oral cavity, it plays a significant role in preventing oral infections such as periodontal and gum diseases, dental caries, and oral candidiasis. The consequences of vitamin D deficiency are bone resorption, increased productions of pro-inflammatory cytokines, T-lymphocytes, increased T-helper-1 functions, and decreased T-helper-2 functions. Consequently, this leads to increased infections, chronic inflammation, and the occurrence of oral diseases such as oral candidiasis, periodontal and gum diseases, and dental caries. The major...Continue Reading

References

Mar 26, 2009·Nature Reviews. Immunology·Susan Moir, Anthony S Fauci
Mar 28, 2009·Journal of Oral Science·Yusuke AmanoMakoto Makishima
Aug 8, 2009·Clinical and Experimental Immunology·A W PedersenM-B Zocca
Jan 11, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Michael Yin, Emily Stein
Jan 17, 2012·Journal of the International Association of Physicians in AIDS Care : JIAPAC·Surasak WiboonchutikulBoonsong Ongphiphadhanakul
Apr 28, 2012·Journal of Dental Research·H Y SroussiM Cohen
Apr 23, 2014·Pediatrics·Robert J SchrothMichael E K Moffatt
Jun 7, 2014·Annals of Pediatric Endocrinology & Metabolism·Se Young Kim
Mar 4, 2015·Brazilian Journal of Otorhinolaryngology·Cleonice Hitomi Watashi Hirata
Apr 9, 2015·Maternal & Child Nutrition·Melissa ZerofskyEllen B Fung
Aug 12, 2015·Antiviral Therapy·Karen M KlassenPeter R Ebeling
Sep 4, 2015·Journal of Clinical and Experimental Dentistry·Gaurav SharmaArchna Nagpal
Nov 11, 2015·Journal of Dental Research·R J SchrothM E Moffatt
Dec 15, 2015·The Journal of Clinical Endocrinology and Metabolism·Gauree Gupta KonijetiAndrew T Chan
Dec 19, 2015·Physiological Reviews·Sylvia ChristakosGeert Carmeliet
Feb 18, 2016·Oral Diseases·V YengopalM P Molete
Feb 19, 2016·Current Opinion in HIV and AIDS·Corrilynn O HilemanGrace A McComsey
Mar 25, 2016·European Journal of Medical Research·Armin ZittermannWinfried März
Apr 11, 2017·Journal of the International Association of Providers of AIDS Care·Sebastian NoeEva Wolf
Sep 14, 2017·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Allison Ross EckardGrace A McComsey
Oct 6, 2017·The Open Orthopaedics Journal·Aamir N AhmadNafees Ahmad
Aug 31, 2018·Journal of Oral and Maxillofacial Pathology : JOMFP·Mvr RatnamSania Md Azmi
Oct 23, 2018·Medicina·Eglė JagelavičienėGoda Daugėlaitė
Sep 19, 2019·Mediators of Inflammation·Lili WeiHaofei Xiong
Feb 6, 2020·Infection and Drug Resistance·Birhanu AyelignGashaw Dessie
Feb 8, 2020·International Journal of Environmental Research and Public Health·Maria Grazia CagettiGuglielmo Campus
Apr 2, 2020·The Journal of Steroid Biochemistry and Molecular Biology·Nuraly S AkimbekovMohammed S Razzaque
May 2, 2020·Nutrients·Pieter-Jan MartensAnd Chantal Mathieu
May 23, 2020·Nutrients·João BotelhoJosé João Mendes
Jul 17, 2020·Archives of Oral Biology·Batuhan A BayirliBahattin Avci
Jul 28, 2020·Nutrients·Vanessa MachadoJoão Botelho
Sep 25, 2020·Nutrients·Maheen SiddiquiHadi M Yassine
Oct 18, 2020·International Journal of Molecular Sciences·Monica CurròRiccardo Ientile

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