PMID: 6412158Sep 1, 1983Paper

The renal origin of sodium valproate-induced hyperammonemia in fasting humans

Neurology
J M WarterM Imler

Abstract

Acute administration of 1,500 mg of sodium valproate or chronic administration of 30 mg/kg/24 hours induced a more than twofold increase of renal ammoniagenesis in fasting subjects. Hyperammonemia was moderate, as normal hepatic ammonia detoxification persisted. Renal uptake of glutamine increased simultaneously.

Citations

Jun 19, 1992·Pharmaceutisch Weekblad. Scientific Edition·J R Stephens, R H Levy
Apr 1, 1991·Italian Journal of Neurological Sciences·S GentileI Sacerdote
Feb 1, 1987·Neurochemical Pathology·A J Cooper, J C Lai
Dec 12, 2007·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Abhishek Katiyar, Cynthia Aaron
Oct 15, 1989·Biochemical Pharmacology·M CulebrasJ M López-Novoa
Apr 16, 1986·European Journal of Pharmacology·M ImlerJ M Warter
Jul 1, 1985·Journal of the Neurological Sciences·J M WarterM Imler
Jan 1, 1995·Pharmacology & Therapeutics·B Fromenty, D Pessayre
Aug 1, 1990·Toxicology·R M WalkerG E Macallum
Sep 16, 1999·Biochemical Pharmacology·E I ZagryadskayaA A Nikiforov
Apr 18, 1987·Lancet·M HjelmJ D Kay
May 22, 2002·Neurochemistry International·Steven W M Olde DaminkRajiv Jalan
Jul 11, 2009·The Journal of Trauma·Akiyoshi Hagiwara, Toshihisa Sakamoto
Jun 18, 2009·Diabetes, Obesity & Metabolism·V Walker
Jan 4, 1986·British Medical Journal·M HjelmC J Rolles
Nov 10, 2005·Critical Care : the Official Journal of the Critical Care Forum·Philippe E R LheureuxMireille Gris
Sep 3, 2009·Case Reports in Medicine·Vikrant MittalRajesh R Tampi
Oct 24, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Steven W M Olde DaminkPeter B Soeters
Jun 1, 1989·Metabolic Brain Disease·L Zieve, C Lyftogt
Feb 18, 2011·Expert Opinion on Drug Safety·Sherifa A Hamed
Mar 13, 2009·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Philippe E R Lheureux, Philippe Hantson
Sep 1, 1987·Medical Toxicology and Adverse Drug Experience·M J Eadie
Mar 1, 1988·Medical Toxicology and Adverse Drug Experience·M J EadieR G Dickinson
Nov 1, 1988·Kidney International·M Rengel-ArandaJ M Lopez-Novoa
Mar 21, 2009·Epilepsy Research·Jennifer L DeWolfeNita A Limdi
Aug 9, 2011·Anesthesia and Analgesia·Dmitri BezinoverPiotr K Janicki
Jun 28, 2011·Epilepsy & Behavior : E&B·Asier Gomez-IbañezCesar Viteri-Torres
May 14, 2016·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·I David Weiner
Jan 1, 1991·Journal of Child Neurology·D L Coulter
Oct 6, 2010·Journal of Child Neurology·Suvasini SharmaYogender Kumar Gupta
Mar 30, 2005·Journal of Child Neurology·Eddie CheungCheuk-Wing Fung
May 1, 1993·The Annals of Pharmacotherapy·J DuarteL E Clavería
Dec 11, 2008·Metabolic Brain Disease·Steven W M Olde DaminkCornelius H C Dejong
Mar 25, 2010·American Journal of Physiology. Endocrinology and Metabolism·Jason R TrebergJohn T Brosnan
Jan 1, 1996·Scandinavian Journal of Gastroenterology. Supplement·C H DejongP B Soeters
Aug 17, 2005·Arquivos de neuro-psiquiatria·Marlene de Fátima TurcatoCarolina Araújo Rodrigues Funayama
Feb 6, 2017·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Verena SchrettlFlorian Eyer
Jan 30, 2004·The American Journal of Clinical Nutrition·Marcel C G van de PollCornelis H C Dejong
Mar 16, 2004·Acta Neurologica Scandinavica·C-M LokrantzF Asztely

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