The representation of biological classes in the human brain.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Andrew C ConnollyJames V Haxby

Abstract

Evidence of category specificity from neuroimaging in the human visual system is generally limited to a few relatively coarse categorical distinctions-e.g., faces versus bodies, or animals versus artifacts-leaving unknown the neural underpinnings of fine-grained category structure within these large domains. Here we use fMRI to explore brain activity for a set of categories within the animate domain, including six animal species-two each from three very different biological classes: primates, birds, and insects. Patterns of activity throughout ventral object vision cortex reflected the biological classes of the stimuli. Specifically, the abstract representational space-measured as dissimilarity matrices defined between species-specific multivariate patterns of brain activity-correlated strongly with behavioral judgments of biological similarity of the same stimuli. This biological class structure was uncorrelated with structure measured in retinotopic visual cortex, which correlated instead with a dissimilarity matrix defined by a model of V1 cortex for the same stimuli. Additionally, analysis of the shape of the similarity space in ventral regions provides evidence for a continuum in the abstract representational space-with pr...Continue Reading

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Citations

May 2, 2012·Computational and Mathematical Methods in Medicine·Hervé AbdiJames V Haxby
Feb 16, 2013·Journal of Cognitive Neuroscience·Bradford Z MahonJorge Almeida
Jun 21, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Talia Konkle, Alfonso Caramazza
Jul 12, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Ning LiuLeslie G Ungerleider
Apr 5, 2014·BioMed Research International·Giuliana NapolitanoBarbara Majello
Oct 31, 2013·Journal of Cognitive Neuroscience·Andrew J AndersonMassimo Poesio
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Feb 18, 2016·ELife·Andrea LeoEmiliano Ricciardi
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Oct 1, 2014·Journal of Cognitive Neuroscience·Long ShaAndrew C Connolly

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