PMID: 9430798Feb 7, 1998Paper

The reproducibility of cardiac baroreceptor activity assessed non-invasively by spectral sequence techniques

Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society
S L DawsonJ F Potter

Abstract

Baroreceptor sensitivity (BRS) is increasingly used as a prognostic indicator in cardiovascular disease. Traditionally it has been measured using invasive techniques with pharmacological manipulation of blood pressure (BP). With the advent of newer methods to measure pulse interval and beat-to-beat changes in BP it is now possible, using sophisticated mathematical modelling techniques, to calculate cardiac BRS non-invasively. However, there are virtually no data on the reproducibility of these newer techniques and what factors may affect the repeatability of these measurements. We studied 39 subjects, aged 22-82 years, with a supine systolic BP range 97-160 mmHg and a diastolic BP range 57-94 mmHg on two occasions between 1 week and 6 months apart. Cardiac BRS was measured by power spectral analysis using Fast Fourier Transformation (FFT), sequence analysis (using up, down and combined sequences) and from phase IV of the Valsalva manoeuvre. There was no significant difference between visits for any of the methods for measuring cardiac BRS. Mean BRS values were similar for FFT (16.7 +/- 11.2 ms/mmHg) and sequence analysis (15.8 +/- 11.4 ms/mmHg); however, results using phase IV of the Valsalva manoeuvre were significantly lower ...Continue Reading

References

Aug 1, 1991·Circulation·A MallianiS Cerutti
Oct 1, 1971·Circulation Research·B GribbinR Peto
Dec 1, 1996·Hypertension·M A JamesJ F Potter
Apr 1, 1997·The American Journal of Physiology·R B PaneraiJ F Potter

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Citations

Mar 16, 2005·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Sinsia A GaoPeter Friberg
Mar 16, 2005·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Mark W Chapleau
Jun 14, 2006·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Paul JohnsonMartin James
Jun 18, 2010·Biological Psychology·Andrea DietrichHarriëtte Riese
Feb 28, 2001·Diabetes, Obesity & Metabolism·P G McNallyH Thurston
Jul 21, 1998·Annals of the New York Academy of Sciences·T J Novitsky
Nov 5, 2003·Journal of Hypertension·Christina AbrahamssonLars Lind
Dec 1, 2008·NDT Plus·Chris W McIntyreHelen J Jefferies

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