PMID: 2111153Mar 1, 1990Paper

The responses of superior laryngeal nerve afferent fibres to laryngeal airway CO2 concentration in the anaesthetized cat

Experimental Physiology
A BradfordR G O'Regan

Abstract

In anaesthetized cats, the isolated, in situ, larynx was subjected to a simulated respiratory cycle and the responses of fifty-six superior laryngeal nerve (SLN) afferent fibres to respiration-related stimuli were examined during changes in the fractional CO2 concentration of the laryngeal airway (Faw, CO2). Sensory SLN fibres which displayed low rates of discharge when the larynx was unventilated (quiescent fibres) and which responded to negative laryngeal airway pressure were excited by elevations in Faw, CO2 whereas quiescent fibres responsive to positive laryngeal pressure were inhibited by the same procedure. We propose that changes in airway CO2 levels may play a role in maintaining upper airway patency, especially during sleep.

Citations

Apr 1, 1996·Respiration Physiology·E L CoatesD Bartlett
Apr 1, 1994·Respiration Physiology·D Bartlett, S L Knuth
Mar 30, 2004·Autonomic Neuroscience : Basic & Clinical·Kazutoshi NishijimaYasuro Atoji
Jan 30, 2007·Respiration; International Review of Thoracic Diseases·A RazaA Bradford
Dec 1, 1994·Pflügers Archiv : European journal of physiology·K D O'HalloranA Bradford
Sep 8, 1998·Journal of Applied Physiology·A BradfordR G O'Regan
Apr 6, 2000·Journal of Applied Physiology·R B FogelD P White

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