The results of esophagogastrectomy without thoracotomy for adenocarcinoma of the esophagogastric junction.

Annals of Surgery
R J Finley, R I Inculet

Abstract

Between 1980 and 1988, 98 patients with adenocarcinoma of the esophagogastric junction were seen at the University of Western Ontario. Eighty-two patients underwent resection of the celiac lymph nodes, lesser curve and cardia of the stomach, and thoracic esophagus through abdominal and neck incisions avoiding thoracotomy. The esophagus was replaced by a stomach tube in 80 patients or by a colon tube in two patients. Two of 82 patients died while hospitalized. Early postoperative morbidity included anastomotic leaks that closed spontaneously (13), transient hoarseness (10), myocardial infarction (2), pulmonary embolus (6), and atelectasis or pneumonia (13). Late postoperative complications included delayed gastric emptying (4), symptomatic reflux (4), diarrhea (10), and anastomotic strictures (17). The 2-year survival of 30% was significantly affected by the stage of disease (p = 0.003), depth of tumor penetration (p = 0.02), lymph node metastasis (p = 0.001), tumor differentiation (p = 0.008), and tumor DNA ploidy (p = 0.02). Local recurrences appeared initially in 20 patients: anastomotic (3), peritoneal (14), mediastinal (3); distant metastasis occurred in 27 patients: bone (15), liver (5), brain (2), and multiple organs (5)....Continue Reading

References

Oct 1, 1986·Annals of Surgery·D B SkinnerV M Staszak
Apr 1, 1988·World Journal of Surgery·J Moreaux, S Msika
Feb 1, 1983·The Annals of Thoracic Surgery·P Wang, K Chien
Jul 1, 1980·Annals of Surgery·D N Papachristou, J G Fortner

❮ Previous
Next ❯

Citations

May 1, 1997·Journal of Surgical Oncology·M Noguchi, I Miyazaki
Jun 1, 1992·Journal of Surgical Oncology·J A Roth
Dec 1, 1992·Journal of Surgical Oncology·J S BoltonJ K Ellis
Sep 1, 1993·Journal of Surgical Oncology·N TanigawaR Muraoka
Sep 1, 1995·Journal of Surgical Oncology·A G CassonF O'Malley
Jan 1, 1990·Seminars in Surgical Oncology·D P KelsenM Burt
Mar 1, 1995·World Journal of Surgery·J A Roth
May 1, 1994·World Journal of Surgery·N K AltorkiD B Skinner
May 1, 1994·World Journal of Surgery·K TakeshitaM Endo
May 29, 2004·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·N M BösingH-D Röher
Aug 5, 2008·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Diego AvellaKevin Staveley-O'Carroll
May 1, 1996·European Journal of Radiology·H van Overhagen
Nov 5, 1997·The Surgical Clinics of North America·R B Lee, J I Miller
Feb 24, 2001·Current Problems in Cancer·R Wong, R Malthaner
Nov 12, 2002·Surgical Oncology Clinics of North America·John S Bolton, Steve Teng
Sep 13, 2001·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·S MattioliW F Grigioni
Feb 27, 2001·Annals of Surgery·B P WijnhovenW N Dinjens
Jun 23, 2001·Annals of Surgery·J M CollardP J Kestens
Jun 7, 2002·Gut·W H AllumUNKNOWN British Association of Surgical Oncology
Oct 1, 1993·The Annals of Thoracic Surgery·W T VigneswaranM S Allen
May 29, 2007·The Annals of Thoracic Surgery·Paul D DiMusto, Mark B Orringer
Jun 23, 2009·Journal of Surgical Oncology·Yi-Jen ChenKemp H Kernstine
Dec 1, 1991·American Journal of Surgery·M G PattiC A Pellegrini
Oct 18, 2001·The Annals of Thoracic Surgery·J A Hagen, T R DeMeester
Jul 1, 1992·The Annals of Thoracic Surgery·A W HemmingG Fradet
Mar 1, 1996·The Journal of Thoracic and Cardiovascular Surgery·M BurtR J Ginsberg
Jul 26, 2005·The Annals of Thoracic Surgery·Hyun-Sung LeeJae Ill Zo
Nov 19, 2002·Revista do Hospital das Clínicas·Andrea CariatiGianluigi Pescio
Mar 1, 1994·The British Journal of Surgery·D AldersonR H Kennedy

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.