Abstract
Skin cancer patients with nonmelanoma skin cancer who have the highest risk of disease-specific death are squamous cell carcinoma (SCC). The aim of this study is to determine the characteristics (age, sex), indications, and doses of lesions and radiotherapy (RT), locoregional control (LRC), relapse-free survival (RFS), and overall survival (OS) rates in SCCs of the skin patients treated and followed at our clinic. For this purpose, 153 patients treated with RT and followed between 1996, January and 2018, December were included in the study. Of the patients, 95 (62%) were men and 58 (38%) woman. The mean age was 56.4 ± 13.9 (44-93) years. The primary tumor sites were 132 (86%) head and neck, 12 (8%) extremity and 9 (6%) trunk. The 3-year LRC, RFS, and OS rates were 88% (95% confidence interval [CI]: 82-98), 87% (95% CI: 80-96), and 92% (95% CI: 88-98), respectively. Men gender received significantly worse prognosis than female sex (p = .02). The recurrence-free rate of tumors 2 cm or smaller was significantly lower than tumors larger than 2 cm (p < .001). Cosmetic results were good in 29% of the patients, fair in 50%, and poor in 21%. RT plays an integral role in the treatment of primary and postoperative SCCs.
References
Apr 18, 2002·International Journal of Radiation Oncology, Biology, Physics·May N TsaoLorne Rotstein
May 7, 2004·The New England Journal of Medicine·Jay S CooperUNKNOWN Radiation Therapy Oncology Group 9501/Intergroup
May 7, 2004·The New England Journal of Medicine·Jacques BernierUNKNOWN European Organization for Research and Treatment of Cancer Trial 22931
Sep 24, 2004·International Journal of Radiation Oncology, Biology, Physics·Winkle KwanVeronika Moravan
Feb 1, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Gary L ClaymanScott M Lippman
May 4, 2005·The Laryngoscope·Michael J VenessVal Gebski
Aug 22, 2006·Histopathology·P J F QuaedvliegG A Krekels
Nov 16, 2007·Journal of Cutaneous Pathology·Jag Bhawan
Apr 22, 2008·American Journal of Epidemiology·I SoerjomataramE de Vries
Jul 12, 2008·The Lancet Oncology·Kay D BrantschHelmut Breuninger
Aug 19, 2009·The Laryngoscope·William M MendenhallNancy P Mendenhall
Nov 24, 2011·Head & Neck·Jeffrey T WangMichael J Veness
Aug 15, 2013·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Rebecca K S WongMario E Lacouture