The retinal targets of centrifugal neurons and the retinal neurons projecting to the accessory optic system

Visual Neuroscience
D L NicklaJ Wallman

Abstract

In birds, neurons of the isthmo-optic nucleus (ION), as well as "ectopic" neurons, send axons to the retina, where they synapse on cells in the inner nuclear layer (INL). Previous work has shown that centrifugal axons can be divided into two anatomically distinct types depending on their model of termination: either "convergent" or "divergent" (Ramon y Cajal, 1889; Maturana & Frenk, 1965). We show that cytochrome-oxidase histochemistry specifically labels "convergent" centrifugal axons and target neurons which appear to be amacrine cells, as well as three "types" of ganglion cells: two types found in the INL (displaced ganglion cells) and one in the ganglion cell layer. Labeled target amacrine cells have distinct darkly labeled "nests" of boutons enveloping the somas, are associated with labeled centrifugal fibers, and are confined to central retina. Lesions of the isthmo-optic tract abolish the cytochrome-oxidase labeling in the centrifugal axons and in the target amacrine cells but not in the ganglion cells. Cytochrome-oxidase-labeled ganglion cells in the INL are large; one type is oval and similar to the classical displaced ganglion cells of Dogiel, which have been reported to receive centrifugal input; the other type is ro...Continue Reading

References

Apr 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·J H KartenN Brecha
Nov 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·P G Clarke, W M Cowan
Feb 1, 1976·The Journal of Physiology·P L Marchiafava
Mar 1, 1976·The Journal of Comparative Neurology·A L Pearlman, C P Hughes
Mar 1, 1976·The Journal of Comparative Neurology·A L Pearlman, C P Hughes
Jan 1, 1990·Experimental Brain Research·G MarinJ Wallman
Mar 1, 1989·Trends in Neurosciences·M T Wong-Riley
Apr 1, 1989·Neuroscience Research·F A PradaJ M Génis-Gálvez
Sep 1, 1989·Visual Neuroscience·H Uchiyama
Nov 8, 1988·The Journal of Comparative Neurology·A E Mjaatvedt, M T Wong-Riley
Jan 1, 1966·Zeitschrift für Zellforschung und mikroskopische Anatomie·J E Dowling, W M Cowan
Jan 10, 1981·The Journal of Comparative Neurology·K V FiteS P Hunt

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Citations

Feb 22, 2000·Behavioural Brain Research·D MiceliJ P Rio
Mar 10, 2000·Brain Research Bulletin·J HuS R Wang
May 15, 2009·Visual Neuroscience·S H LindstromMartin Wilson
Jul 24, 2010·Visual Neuroscience·Sarah H LindstromMartin Wilson
Apr 29, 2011·Visual Neuroscience·Martin Wilson, Sarah H Lindstrom
May 11, 2011·Visual Neuroscience·Martin WilsonDavid I Vaney
Apr 30, 2013·Journal of Integrative Neuroscience·Igor I Pushchin
Dec 30, 2014·Neuroscience and Biobehavioral Reviews·O Rosa SalvaG Vallortigara
Dec 4, 2003·The Journal of Comparative Neurology·Monique MédinaDom Miceli
May 27, 2015·The Journal of Comparative Neurology·Anahit HovhannisyanThomas A Münch
Jul 22, 2014·The Journal of Comparative Neurology·Douglas R WylieCristian Gutierrez-Ibanez
Sep 1, 2015·Frontiers in Neuroscience·Douglas R WylieAndrew N Iwaniuk
Sep 6, 2000·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·K C Calaza, P F Gardino
Mar 4, 2017·The Journal of Comparative Neurology·Quirin KrabichlerHarald Luksch
Oct 1, 1998·Veterinary Pathology·K ShibuyaT Nunoya
Dec 23, 2003·The Journal of Comparative Neurology·U DrenhausG Rager
Jul 13, 2004·The Journal of Comparative Neurology·Hiroyuki UchiyamaHiroshi Ohno
Feb 14, 2006·Visual Neuroscience·H Uchiyama, W K Stell
Nov 27, 1995·The Journal of Comparative Neurology·W WoodsonH J Karten

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