The Rising Frequency of Continuous Deep Sedation in the Netherlands, a Repeated Cross-Sectional Survey in 2005, 2010, and 2015.

Journal of the American Medical Directors Association
Judith RietjensAgnes van der Heide

Abstract

In the Netherlands, the use of continuous deep sedation at the end of life has sharply increased from 8.2% of all deaths in 2005 to 12.3% in 2010 to 18.3 % in 2015. We describe its clinical characteristics in 2015 and compare it with 2010 and 2005. Questionnaire study in random samples of death reported to a central death registry. A nationwide study in the Netherlands among physicians attending reported deaths. Continuous deep sedation characteristics (patient characteristics, drugs, duration, estimated shortening of life, and palliative consultation) from the Netherlands in 2015 were compared with continuous deep sedation characteristics of 2010 and 2005. The response rate was 78% (n = 7277) in 2015, 74% (n = 6263) in 2010, and 78% (n = 6860) in 2005. The increased frequency of continuous deep sedation was notable in all patient subgroups, but mainly occurred among deaths attended by general practitioners, particularly in patients older than 80 years and patients with cancer. In 2015, continuous deep sedation was performed in 93% of the patients through administration of benzodiazepines. In 3% of the patients, the sedation lasted more than 1 week. Furthermore, 60% of the physicians reported that they had no intention to haste...Continue Reading

References

Apr 3, 2007·Journal of Medical Ethics·Johannes J M van Delden
Jul 10, 2007·Journal of Pain and Symptom Management·Marian VerkerkAlexander de Graeff
Mar 18, 2008·BMJ : British Medical Journal·Judith RietjensAgnes van der Heide
Mar 11, 2009·Archives of Internal Medicine·Jeroen G J HasselaarKris C P Vissers
Oct 28, 2009·Palliative Medicine·Nathan I ChernyUNKNOWN Board of the European Association for Palliative Care
Mar 10, 2010·Archives of Internal Medicine·Kenneth ChambaereLuc Deliens
Mar 14, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Marco MaltoniOriana Nanni
May 15, 2013·Current Opinion in Oncology·Marco MaltoniOriana Nanni
Sep 17, 2013·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Ian KoperJudith Rietjens
Jan 15, 2014·Journal of Palliative Medicine·Siebe J SwartJudith A C Rietjens
Sep 1, 2012·BMJ Supportive & Palliative Care·Siebe J SwartJudith Rietjens
May 9, 2014·The American Journal of Hospice & Palliative Care·Lauren GurschickLaura C Hanson
Sep 15, 2014·HEC Forum : an Interdisciplinary Journal on Hospitals' Ethical and Legal Issues·Margreet StolperGuy Widdershoven
Mar 2, 2016·JAMA Internal Medicine·Georg BosshardKarin Faisst
Aug 3, 2017·The New England Journal of Medicine·Agnes van der HeideBregje D Onwuteaka-Philipsen

❮ Previous
Next ❯

Citations

Oct 13, 2020·Journal of the American Medical Directors Association·Eva SchildmannClaudia Bausewein
Aug 2, 2021·Journal of Pain and Symptom Management·Madelon T HeijltjesJudith A C Rietjens

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.