PMID: 9161811Feb 1, 1997Paper

The risk factor profile of recto-sigmoid adenomas: a prospective screening study of 665 patients in a clinical rehabilitation centre

European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)
B ManusR W Stockbrügger

Abstract

During a prospective screening study for recto-sigmoid adenomatous polyps, the influence of the following risk factors was evaluated: age; gender; body mass index; heredity for colorectal malignancy; diabetes; hypertension; constipation; previous gastric surgery; previous gastric acid inhibition; alcohol and cigarette consumption; serum cholesterol; serum triglycerides; and serum gastrin. Screening fibre-sigmoidoscopy of 665 patients (aged between 50 and 60 years) at a clinical rehabilitation centre for gastrointestinal and metabolic diseases showed that 146 had one or several adenomas. The study population was overweight by a mean of about 15%. Comparison of those with and those without adenoma using univariate analysis, showed that the group with adenomas had higher serum triglyceride values, drank more alcohol on a regular or excessive basis, were more frequent smokers, and had a tendency to raised fasting serum glucose. In a multivariate analysis, age, high serum triglycerides and high alcohol consumption were risk factors for recto-sigmoid adenomas. The risk factor profile identified in this study may help in the selection of individuals for screening sigmoidoscopy from a similar background population. It also identifies t...Continue Reading

Citations

Nov 18, 2006·Cancer Causes & Control : CCC·Tetsuya OtaniShoichiro Tsugane
Apr 24, 2009·Cancer Causes & Control : CCC·Michael F LeitzmannAmanda J Cross
Apr 26, 2003·Mutation Research·Anja SchaeferhenrichBeatrice Louise Pool-Zobel
Oct 27, 2011·Biochemistry Research International·Shinji TakasuHitoshi Nakagama
Aug 25, 2001·The British Journal of Nutrition·F BrancaH Verhagen
Feb 23, 2008·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·M K JungJ M Chung
Nov 8, 2013·Gastroenterology Research and Practice·Wen YangXiaohong Yu
Jun 5, 2003·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·J Santavirta
Feb 8, 2005·Laboratory Investigation; a Journal of Technical Methods and Pathology·Jochen Wedemeyer, Stephen J Galli
Jul 23, 2011·Archives of Animal Nutrition·Fathy Abdel-Fattah, Wolfgang Gaede
Feb 13, 2008·The American Journal of Clinical Nutrition·Edward Giovannucci

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