Abstract
There is little information on the incidence and predictors of infarction, stroke, or cardiovascular death after acute coronary syndrome. We investigated these aspects and developed tools for predicting these events according to the time of their occurrence. A retrospective study was conducted of 4858 patients who survived an acute coronary event. We analyzed the incidence and predictors of acute myocardial infarction, stroke, or cardiovascular death during the first year (n=4858) vs successive years (n=4345 patients free of composite events during the first year). There were 329 events in the first year (cumulative incidence function: 7.3% person-years) and 616 in successive years (21.5% person-years; follow-up 4.9±2.4 years). The risk of events during the first year per tertile was 2.5% person-years in the low-risk tertile (< 3 points), 4.8% person-years in the intermediate-risk tertile (3-6 points), and 15.5% person-years in the high-risk tertile (> 6 points) (P<.001). The risk of events in the cohort that had a combined event in successive years increased from 10.7% person-years in the low-risk tertile (< 3 points) to 40.3% person-years in the high-risk tertile (> 6 points) (P<.001). The 2 scales showed the following predic...Continue Reading
References
Dec 22, 1999·International Journal of Epidemiology·P RoystonW Sauerbrei
May 4, 2004·Statistics in Medicine·Lisa M SullivanRalph B D'Agostino
Jun 10, 2004·JAMA : the Journal of the American Medical Association·Kim A EagleUNKNOWN GRACE Investigators
Nov 3, 2005·Annals of Internal Medicine·Alexander M ClarkFinlay A McAlister
Oct 13, 2006·BMJ : British Medical Journal·Keith A A FoxChristopher B Granger
Nov 30, 2006·PLoS Medicine·Colin D Mathers, Dejan Loncar
Mar 16, 2007·Current Medical Research and Opinion·Matthew J TaylorDavid E Newby
Nov 6, 2007·The New England Journal of Medicine·Stephen D WiviottUNKNOWN TRITON-TIMI 38 Investigators
Nov 27, 2008·American Heart Journal·William J RogersWilliam J French
Nov 27, 2008·American Heart Journal·Lilian Grigorian-ShamagianJose Ramon Gonzalez-Juanatey
Jul 17, 2010·Journal of the American College of Cardiology·Matthew T RoeJohn S Rumsfeld
Sep 2, 2010·European Heart Journal·Keith A A FoxFrans Van de Werf
Sep 2, 2010·JAMA : the Journal of the American Medical Association·Deepak L BhattUNKNOWN REACH Registry Investigators
Aug 2, 2011·Revista española de cardiología·Fernando ArósUNKNOWN en representación de los investigadores de los registros PRIAMHO I, II y MASCARA
Nov 24, 2012·JACC. Cardiovascular Interventions·Sergio Raposeiras-RoubínJosé Ramón González-Juanatey
Jan 28, 2014·Lancet·Sheng-Chia ChungHarry Hemingway
Aug 21, 2014·European Heart Journal·Melanie NicholsMike Rayner
Nov 18, 2014·The New England Journal of Medicine·Laura MauriUNKNOWN DAPT Study Investigators
Jan 15, 2015·European Heart Journal·Tomas JernbergMagnus Janzon
Mar 17, 2015·The New England Journal of Medicine·Marc P BonacaUNKNOWN PEGASUS-TIMI 54 Steering Committee and Investigators
Mar 17, 2015·The New England Journal of Medicine·Jennifer G RobinsonUNKNOWN ODYSSEY LONG TERM Investigators
Apr 16, 2015·Circulation. Cardiovascular Interventions·Sripal BangaloreJørn Wetterslev
Sep 24, 2015·The New England Journal of Medicine·Marc P BonacaMarc S Sabatine
Citations
Oct 27, 2016·Revista Española De Cardiología·Manuel Anguita SánchezLuis Rodríguez Padial
Mar 23, 2017·International Heart Journal·Lu YihuaZhao Dongshen
Apr 27, 2017·European Heart Journal. Cardiovascular Pharmacotherapy·Cengiz ÖzcanGunnar Hilmar Gislason
Feb 23, 2020·Journal of Thrombosis and Thrombolysis·Christina YipMark Y Chan