Abstract
Previous observational studies reported an increased prevalence of asthma in migraine patients. Whether triptans affect the asthma risk has not yet been explored in an epidemiological study. To estimate the risk of newly diagnosed asthma in patients with a general practitioner-diagnosed migraine in the UK between 1994 and 2001. A population-based follow-up study and a nested case-control analysis were conducted using the General Practice Research Database. The study encompassed 51,688 migraineurs and the same number of matched controls. In the follow-up analysis, the relative risk of developing asthma in migraineurs compared with non-migraineurs was 1.3 (95% confidence interval [CI] 1.1-1.4). In the nested case-control analysis, the adjusted odds ratio for asthma in migraineurs overall was 1.17 (95% CI 1.01-1.35), and for those with a recent triptan prescription 1.12 (95% CI 0.65-1.94). The risk of developing asthma was not materially altered for patients with a general practitioner-recorded migraine diagnosis, regardless of triptan use.
References
Jul 25, 1980·European Journal of Pharmacology·B B VargaftigJ Benveniste
May 11, 1996·BMJ : British Medical Journal·D P StrachanH R Anderson
Sep 1, 1996·British Journal of Pharmacology·M R MacLeanI Morecroft
Dec 1, 1996·Cephalalgia : an International Journal of Headache·W H VisserM D Ferrari
Dec 31, 1997·Neurology·N T MathewA Laurenza
May 1, 1998·Headache·V PfaffenrathS Prendergast
Apr 23, 1999·Lancet·H Jick
Dec 23, 1999·Current Opinion in Pulmonary Medicine·A Fogarty, J Britton
Feb 13, 2001·Cephalalgia : an International Journal of Headache·K M WelchD Gutterman
Sep 7, 2002·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Julie Von BehrenAlexandra Hernandez
Mar 27, 2003·Pediatric Neurology·J Gordon Millichap, Michelle M Yee
Jul 22, 2004·Cephalalgia : an International Journal of Headache·P SarchielliV Gallai
Sep 16, 2004·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Louise Wood, Carlos Martinez
Apr 5, 2005·Family Practice·Louise WatsonDirkje S Postma
Feb 16, 2007·Headache·Anne H AamodtJohn-Anker Zwart
Citations
Feb 24, 2012·Current Allergy and Asthma Reports·Mark E Mehle
Jan 7, 2014·Network Modeling and Analysis in Health Informatics and Bioinformatics·Meng-Han YangYen-Jen Oyang
Mar 8, 2017·The Clinical Respiratory Journal·Yi-Hao PengWen-Chao Ho
Aug 19, 2018·Neurologia i neurochirurgia polska·Mehdi SayyahFakher Rahim
Feb 2, 2021·Frontiers in Medicine·Long WangYu Wang