The Risk of Retinopathy of Prematurity in the Infants following Assisted Reproductive Technology: A Meta-Analysis

BioMed Research International
Lixiong GaoQian Shi

Abstract

Currently, the use of assisted reproductive technology (ART) is increasing. Because of the poor prognosis of retinopathy of prematurity (ROP), the association between ART and the ROP has been explored in several studies, but the result was still inconclusive. Conducting a meta-analysis, we evaluated the risk of ROP in relation to the ART. Subgroup analysis as well as groups with different embryo numbers and different ROP stages was further analyzed. The PubMed, Embase, and Cochrane Library databases were searched for studies recording data about both the use of ART and ROP occurrence simultaneously. Odds ratios (ORs) and 95% confidence interval (95%CI) were calculated to analyze the association by using random- or fixed-effect models based on heterogeneity test. In total 15 observational studies containing 10392 ART cases and 39474 spontaneous conception cases were included. Results showed that there was a significant association between the use of ART and ROP occurrence in the offspring (OR = 1.34, 95% CI: 1.05 to 1.73, P = 0.02). With subgroup analysis, we found that the influence actually came from a subgroup of ART, the in vitro fertilization (IVF). Moreover, there was a significant association between ART and ROP in single...Continue Reading

References

Jan 1, 1996·Eye·M McKibbin, T R Dabbs
Mar 8, 2002·The New England Journal of Medicine·Laura A SchieveLynne S Wilcox
Nov 30, 2004·Human Reproduction·Michèle HansenJennifer J Kurinczuk
Jul 5, 2005·Pediatrics·William V GoodUNKNOWN Early Treatment for Retinopathy of Prematurity Cooperative Group
Mar 14, 2007·Current Opinion in Obstetrics & Gynecology·Neelanjana Mukhopadhaya, Sabaratnam Arulkumaran
Jan 8, 2008·Lancet·Robert L GoldenbergRoberto Romero
Jul 7, 2009·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Sarah D McDonaldUNKNOWN Knowledge Synthesis Group
Oct 22, 2010·Current Opinion in Endocrinology, Diabetes, and Obesity·Lawrence N Odom, James Segars
May 31, 2011·Early Human Development·Vasileios GiaprosStyliani Andronikou
Feb 1, 2012·Pediatrics·Kenneth D KochanekBernard Guyer
Apr 12, 2012·Archives of Ophthalmology·Jennifer HuRashmi Kapur
Jun 21, 2013·Lancet·Ann HellströmOlaf Dammann
Aug 30, 2013·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Lucia MireaUNKNOWN Canadian Neonatal Network
May 9, 2014·Molecular Reproduction and Development·Juan J TarínAntonio Cano
Dec 30, 2014·American Journal of Perinatology·Laura ChiarelliUNKNOWN ; on behalf of the Canadian Neonatal Network
Jul 5, 2017·Indian Journal of Pediatrics·Mangat Ram DograMohit Dogra
Nov 9, 2017·Human Reproduction·UNKNOWN European IVF-monitoring Consortium (EIM)V Goossens
Feb 3, 2018·Investigative Ophthalmology & Visual Science·Tian WuDezhi Mu
Apr 22, 2018·Survey of Ophthalmology·Sang Jin KimMichael F Chiang
Jun 9, 2018·American Journal of Perinatology·Jaimin S ShahBaha M Sibai
Dec 19, 2018·Open Access Macedonian Journal of Medical Sciences·Kalina TrifonovaDimitar Dzhelebov
Feb 7, 2019·Journal of Perinatology : Official Journal of the California Perinatal Association·Kaashif Aqeeb AhmadVeeral N Tolia

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Citations

Apr 16, 2020·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Marit L Bovbjerg

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