The road much traveled: trafficking in the cell nucleus

Current Opinion in Cell Biology
Stanislaw A GorskiTom Misteli

Abstract

Trafficking of RNA molecules and proteins within the cell nucleus is central to genome function. Recent work has revealed the nature of RNA and protein motion within the nucleus and across the nuclear membrane. These studies have given insight into how molecules find their destinations within the nucleus and have uncovered some of the structural properties of the nuclear microenvironment. Control of RNA and protein trafficking is now emerging as a physiological regulatory mechanism in gene expression and nuclear function.

References

Dec 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·G Blobel
Jul 14, 1997·The Journal of Cell Biology·O SeksekA S Verkman
May 30, 1998·Proceedings of the National Academy of Sciences of the United States of America·J C PolitzT Pederson
May 18, 1999·The EMBO Journal·N CustódioM Antoniou
May 12, 2000·Journal of Structural Biology·J C Politz, T Pederson
Nov 4, 2000·The Journal of Cell Biology·S SnaarR W Dirks
Feb 24, 2001·Histochemistry and Cell Biology·A B Houtsmuller, W Vermeulen
Dec 6, 2001·Nature Reviews. Molecular Cell Biology·R D Phair, T Misteli
Aug 2, 2002·EMBO Reports·Frédéric CatezMichael Bustin
Sep 5, 2002·Nature Reviews. Cancer·William G Kaelin
Nov 28, 2002·Molecular Cell·Deborah HoogstratenAdriaan B Houtsmuller
Dec 11, 2002·The Journal of Cell Biology·Alexandre CalapezMaria Carmo-Fonseca
Feb 1, 2003·Science·Richard FestensteinDimitris Kioussis
Feb 1, 2003·Science·Thierry CheutinTom Misteli
May 14, 2003·Trends in Cell Biology·Herbert Tschochner, Ed Hurt
Aug 19, 2003·Nature Reviews. Molecular Cell Biology·Angus I Lamond, David L Spector
Aug 30, 2003·EMBO Reports·Pernette J VerschureRoel van Driel
Sep 10, 2003·Molecular Biology of the Cell·Joan C Ritland PolitzThoru Pederson
Sep 23, 2003·Experimental Cell Research·Sabine M GörischPeter Lichter
Mar 17, 2004·The Journal of Cell Biology·Miroslav DundrTom Misteli
Apr 6, 2004·Molecular Biology of the Cell·Lars SchmiedebergPeter Hemmerich
Jun 5, 2004·Nucleic Acids Research·Stephen E Halford, John F Marko
Jun 11, 2004·Biophysical Journal·Brian L SpragueJames G McNally
Jun 19, 2004·Science·Yaron Shav-TalRobert H Singer
Oct 27, 2004·Nature Cell Biology·Gwénaël RabutJan Ellenberg
Jan 7, 2005·Nature·Jens S AndersenMatthias Mann
Jan 20, 2005·The Journal of Cell Biology·Robert Y L Tsai, Ronald D G McKay
Feb 8, 2005·Trends in Cell Biology·Brian L Sprague, James G McNally
Mar 3, 2005·Histochemistry and Cell Biology·M O J Olson, Miroslav Dundr
Apr 16, 2005·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Tom Misteli
Apr 29, 2005·Molecular Biology of the Cell·Joan C Ritland PolitzThoru Pederson
May 20, 2005·Current Opinion in Cell Biology·David L Bentley
May 20, 2005·Current Opinion in Cell Biology·Xavier DarzacqYaron Shav-Tal
Sep 1, 2005·The Journal of Cell Biology·Karim MekhailStephen Lee
Oct 22, 2005·Cell·Kannanganattu V PrasanthDavid L Spector
Oct 26, 2005·Proceedings of the National Academy of Sciences of the United States of America·Darren M GowersStephen E Halford
Nov 15, 2005·Proceedings of the National Academy of Sciences of the United States of America·Diana Y VargasSanjay Tyagi
Dec 1, 2005·Journal of Cell Science·Sabine M GörischKarsten Rippe
Dec 6, 2005·Trends in Cell Biology·Korie E Handwerger, Joseph G Gall

❮ Previous
Next ❯

Citations

Mar 11, 2009·Journal of Mathematical Biology·Moxun Tang
Jul 14, 2010·Chromosoma·Carsten Carlberg, Sabine Seuter
Nov 13, 2007·Histochemistry and Cell Biology·Tom Misteli
Sep 16, 2010·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Thomas DangeDavid Grünwald
Aug 6, 2008·Nature Structural & Molecular Biology·Jason Gorman, Eric C Greene
Jul 27, 2010·Nature Structural & Molecular Biology·Jason GormanEric C Greene
Dec 19, 2009·Proceedings of the National Academy of Sciences of the United States of America·Kitty F VerzijlbergenFred van Leeuwen
Sep 9, 2010·Proceedings of the National Academy of Sciences of the United States of America·Elizabeth HindeEnrico Gratton
Nov 26, 2010·Proceedings of the National Academy of Sciences of the United States of America·Anand D JeyasekharanAshok R Venkitaraman
Sep 27, 2012·Proceedings of the National Academy of Sciences of the United States of America·Jason GormanEric C Greene
Sep 22, 2006·Molecular Biology of the Cell·David GrünwaldUlrich Kubitscheck
Jun 21, 2011·Bioinformatics·Denis C BauerMikael Bodén
Aug 12, 2010·Nucleic Acids Research·Sérgio F de AlmeidaMaria Carmo-Fonseca
Mar 29, 2013·Nucleic Acids Research·Katrin SchneiderLothar Schermelleh
Oct 22, 2010·Cold Spring Harbor Perspectives in Biology·Sami HocineDavid Grünwald
Oct 10, 2007·Molecular and Cellular Biology·Lingjun MengRobert Y L Tsai
Feb 21, 2009·The European Physical Journal. E, Soft Matter·M SuissaE Freyssingeas
Oct 2, 2009·HFSP Journal·Ronen Benjamine Kopito, Michael Elbaum
May 6, 2014·Seminars in Cancer Biology·Asfar S Azmi
Nov 20, 2014·Epigenetics & Chromatin·Lisette C M Anink-GroenenFrank J Bruggeman
Aug 2, 2012·The Journal of Cell Biology·Gero SteinbergMagdalena Martin-Urdiroz
Oct 17, 2007·The Journal of Cell Biology·Noélia CustódioMaria Carmo-Fonseca
Apr 1, 2009·The Journal of Cell Biology·Christoffel DinantRoel van Driel
Sep 12, 2008·Critical Reviews in Oncology/hematology·Pavel TchélidzéDominique Ploton
Aug 12, 2014·Journal of Theoretical Biology·Zuzanna SzymańskaMirosław Lachowicz
May 1, 2007·Current Opinion in Cell Biology·Angela Taddei
Feb 24, 2007·Biochimica Et Biophysica Acta·Klaus D GrasserMarion Grasser
Dec 11, 2007·Biophysical Journal·David GrünwaldM Cristina Cardoso
Jul 9, 2009·Journal of Cellular Biochemistry·Maria-Cristina ArcangelettiCarlo Chezzi
Aug 19, 2015·Nucleus·Robert M MartinM Cristina Cardoso
Feb 18, 2011·Transcription·Carsten Carlberg
Aug 5, 2008·Biochimica Et Biophysica Acta·Ty C Voss, Gordon L Hager
Oct 23, 2012·Genomics, Proteomics & Bioinformatics·Kai WilladsenMikael Bodén
Sep 29, 2009·Molecular Cell·Gordon L HagerTom Misteli
Jul 22, 2009·Biophysical Journal·M SuissaE Freyssingeas
May 7, 2016·Science·Michael Bustin, Tom Misteli
Jan 12, 2017·Biophysical Journal·Anand P SinghTimothy E Saunders
Mar 8, 2008·Human Molecular Genetics·Gareth N CorryD Alan Underhill

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.