The role for high flow nasal cannula as a respiratory support strategy in adults: a clinical practice guideline.

Intensive Care Medicine
Bram RochwergKaren E A Burns

Abstract

High flow nasal cannula (HFNC) is a relatively recent respiratory support technique which delivers high flow, heated and humidified controlled concentration of oxygen via the nasal route. Recently, its use has increased for a variety of clinical indications. To guide clinical practice, we developed evidence-based recommendations regarding use of HFNC in various clinical settings. We formed a guideline panel composed of clinicians, methodologists and experts in respiratory medicine. Using GRADE, the panel developed recommendations for four actionable questions. The guideline panel made a strong recommendation for HFNC in hypoxemic respiratory failure compared to conventional oxygen therapy (COT) (moderate certainty), a conditional recommendation for HFNC following extubation (moderate certainty), no recommendation regarding HFNC in the peri-intubation period (moderate certainty), and a conditional recommendation for postoperative HFNC in high risk and/or obese patients following cardiac or thoracic surgery (moderate certainty). This clinical practice guideline synthesizes current best-evidence into four recommendations for HFNC use in patients with hypoxemic respiratory failure, following extubation, in the peri-intubation perio...Continue Reading

Associated Clinical Trials

Dec 7, 2020·Andrea Cortegiani, MD
Mar 16, 2021·Carlos Augusto Celemín Florez, MD.

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Software Mentioned

GRADE
Revman
Cochrane Risk of Bias
ESCIM

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