The role of 18F-FDG PET in assessing therapy response in cancer of the cervix and ovaries

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
Julie K SchwarzDominique Delbeke

Abstract

For locally advanced cervical cancer, the current literature supports the use of (18)F-FDG PET for assessing treatment response 3 mo after the completion of concurrent chemoradiation. (18)F-FDG PET can provide reliable long-term prognostic information for these patients and, in the future, may be used to guide additional therapy. Investigational areas include the use of (18)F-FDG PET for monitoring response during radiotherapy and chemotherapy in the metastatic and neoadjuvant settings. For ovarian masses, the performance of (18)F-FDG PET in the detection of borderline tumors is limited, and the presence of physiologic (18)F-FDG uptake in normal ovaries of premenopausal women poses another limitation. Preliminary data suggest that the performance of (18)F-FDG PET and (18)F-FDG PET/CT is superior to that of CT alone in initial staging, but the sensitivity of both in the detection of carcinomatosis is limited. Preliminary data also suggest that (18)F-FDG PET may be promising for early prediction of response to chemotherapy and for prediction of response after the completion of chemotherapy. (18)F-FDG PET and (18)F-FDG PET/CT are most helpful in the evaluation of patients with suspected recurrent ovarian carcinoma, especially when...Continue Reading

References

Jan 1, 1992·Cytopathology : Official Journal of the British Society for Clinical Cytology·P W ShieldR G Wright
Sep 1, 1991·International Journal of Radiation Oncology, Biology, Physics·H Hricak
Nov 1, 1989·Gynecologic Oncology·G M SommersM A Lockett
Nov 1, 1994·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·G ScambiaG Puglia
Apr 5, 2000·AJR. American Journal of Roentgenology·K L BergerB A Siegel
Aug 6, 2000·Gynecologic Oncology·D Bodurka-BeversJ T Wharton
Mar 10, 2001·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·W. SchröderW. Rath
Mar 29, 2001·Journal of Magnetic Resonance Imaging : JMRI·E A BossJ O Barentsz
Sep 5, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·P W GrigsbyF Dehdashti
Oct 2, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·M D EsajasA G van der Zee
Jan 5, 2002·International Journal of Radiation Oncology, Biology, Physics·Nina A MayrJohn M Buatti
Mar 22, 2002·The Lancet Oncology·J DoseK H Bohuslavizki
Jul 20, 2002·AJR. American Journal of Roentgenology·Song-Mee ChoJoon Mo Lee
Oct 1, 2003·Clinical Positron Imaging : Official Journal of the Institute for Clinical P.E.T·Gary T. SmithJoseph A. Thie
Mar 3, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Patricia J EifelDavid G Mutch
May 8, 2004·European Journal of Nuclear Medicine and Molecular Imaging·Sungeun KimMyung Chul Lee
Jun 1, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Perry W GrigsbyImran Zoberi
Aug 5, 2004·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Christian MenzelFrank Grünwald
Sep 1, 2004·International Journal of Radiation Oncology, Biology, Physics·Ji-Hong HongSwei Hsueh
Mar 18, 2005·European Journal of Nuclear Medicine and Molecular Imaging·Seok-Ki KimSang-Yoon Park
Mar 26, 2005·Gynecologic Oncology·Laura J HavrileskyEvan R Myers
Apr 26, 2005·Revista española de medicina nuclear·G Ruiz-HernándezJ L Carreras-Delgado
Sep 15, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Norbert AvrilWalther Kuhn
Sep 17, 2005·Clinical Nuclear Medicine·S ShortW Wong
Mar 21, 2006·International Journal of Radiation Oncology, Biology, Physics·Lilie L LinPerry W Grigsby
Apr 22, 2006·Gynecologic Oncology·Bryony SimcockRodney J Hicks
May 24, 2006·Annals of Nuclear Medicine·Hiromasa KurosakiHirotaka Maruno
Sep 2, 2006·Obstetrics and Gynecology·John K ChanKathryn Osann
Nov 8, 2006·European Journal of Nuclear Medicine and Molecular Imaging·Hyun Hoon ChungHyo-Pyo Lee
Dec 21, 2006·European Journal of Nuclear Medicine and Molecular Imaging·G MangiliF Fazio
Feb 24, 2007·European Journal of Nuclear Medicine and Molecular Imaging·María José García-VellosoJosé Angel Richter
Aug 11, 2007·International Journal of Radiation Oncology, Biology, Physics·Franca ForniGiovanni Scambia
Sep 14, 2007·Acta Obstetricia Et Gynecologica Scandinavica·Maria BjurbergEva Brun
Oct 19, 2007·European Journal of Nuclear Medicine and Molecular Imaging·Yoshihiro NishiyamaMotoomi Ohkawa
Nov 22, 2007·JAMA : the Journal of the American Medical Association·Julie K SchwarzPerry W Grigsby
Feb 13, 2008·Journal of the National Comprehensive Cancer Network : JNCCN·Michael A Gold
Feb 22, 2008·CA: a Cancer Journal for Clinicians·Ahmedin JemalMichael J Thun
Jun 10, 2008·International Journal of Radiation Oncology, Biology, Physics·Julie K SchwarzPerry W Grigsby

❮ Previous
Next ❯

Citations

Feb 28, 2013·Journal of Pharmacokinetics and Pharmacodynamics·Giampaolo Tomasi, Eric O Aboagye
Oct 12, 2013·Current Oncology Reports·Tara D BarwickAndrea Rockall
Nov 30, 2010·Annals of Nuclear Medicine·Kazuhiro KitajimaKazuro Sugimura
Jan 12, 2012·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Julie K SchwarzPerry W Grigsby
Jan 23, 2010·AJR. American Journal of Roentgenology·Veena R Iyer, Susanna I Lee
Apr 14, 2011·International Journal of Medical Sciences·Theodor H LippertManfred Volm
Nov 19, 2011·Radiology·G Scott GazelleUNKNOWN Working Group on Comparative Effectiveness Research for Imaging
Aug 21, 2013·Clinical and Experimental Medicine·Dong Hoon SuhYong Sang Song
Sep 14, 2010·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Hongju SonLale Kostakoglu
Dec 3, 2014·PET Clinics·Christina K SpeirsJeffrey D Bradley
Jul 28, 2011·Women's Health·Charlotte RobertsAndrea G Rockall
Sep 19, 2015·European Journal of Nuclear Medicine and Molecular Imaging·Federico CaobelliUNKNOWN Young AIMN Working Group
Aug 21, 2012·Current Opinion in Pharmacology·Giampaolo Tomasi, Lula Rosso
Mar 23, 2011·Obstetrics and Gynecology Clinics of North America·Amnon AmitLior Lowenstein
Apr 1, 2010·PET Clinics·Jacob G Dubroff, Andrew B Newberg
Feb 2, 2010·European Journal of Radiology·Alessandra MustoDomenico Rubello
Jun 9, 2015·Seminars in Nuclear Medicine·Swapnil BagadeFarrokh Dehdashti
Nov 7, 2013·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·B KrugT Vander Borght
Oct 1, 2013·Nuclear Medicine and Biology·Bishnuhari PaudyalEric Wickstrom
Apr 27, 2017·Critical Reviews in Clinical Laboratory Sciences·Khalid El BairiSaid Afqir
Dec 23, 2016·Journal of Biophotonics·Hamid MoradiSangeeta Murugkar
Aug 26, 2017·European Journal of Nuclear Medicine and Molecular Imaging·Theresia SarabhaiJohannes Grueneisen
Jul 28, 2011·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Charles KunosPeter Faulhaber
Jan 10, 2013·Current Opinion in Obstetrics & Gynecology·Amnon AmitZohar Keidar
May 21, 2015·American Society of Clinical Oncology Educational Book·Helen J MackayLinda Mileshkin
Oct 28, 2016·Annals of Nuclear Medicine·Eun Ji HanWoo Hee Choi
Aug 24, 2017·The British Journal of Radiology·Priya Narayanan, Anju Sahdev
Feb 10, 2017·European Journal of Nuclear Medicine and Molecular Imaging·Benjapa KhiewvanAbass Alavi
Aug 5, 2017·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·James C KnightBart Cornelissen
Jan 26, 2021·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Radovan VojtíšekJindřich Fínek
Dec 14, 2011·Clinical Nuclear Medicine·Dimitrios KarantanisJohannes Czernin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.