The role of a leukotriene receptor antagonist in the restoration of the nasal breathing in the patients presenting with polypous rhinosinusitis

Vestnik otorinolaringologii
T A MashkovaL S Bakulina

Abstract

The present study was designed to investigate the clinical. laboratory, and morphological characteristics of the nasal obstruction process. It included 87 patients presenting with polypous rhinosinusitis. The dynamics of the serum leukotriene C4 (LTC4) level in the patients and the morphological changes in their polypous tissue suggested the existence of the pronounced exudative phase of allergic inflammation and provided a basis for the use of the leukotriene receptor antagonist in the form of the sodium montelucast tablets for the treatment of nasal obstruction.

References

Jan 24, 2006·The Annals of Otology, Rhinology, and Laryngology·David A Kieff, Nicolas Y Busaba
May 1, 2010·Current Opinion in Allergy and Clinical Immunology·Gerd Rasp
Nov 2, 2011·Therapeutic Advances in Respiratory Disease·Erkan VuralkanBerrak Ocal
Sep 2, 2015·JAMA : the Journal of the American Medical Association·Luke Rudmik, Zachary M Soler
Sep 20, 2015·Current Allergy and Asthma Reports·Cemal CingiEthem Şahin

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Citations

May 1, 2021·Vestnik otorinolaringologii·N V BoikoN G Nedashkovskaya

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