The role of adjunctive mitomycin C in secondary glaucoma triple procedure as compared to primary glaucoma triple procedure

Ophthalmology
D H ShinK J Yang

Abstract

This study aimed to investigate whether previously failed glaucoma filtration surgery is a risk factor for filtration failure of subsequent trabeculectomy combined with cataract surgery and to determine the role of adjunctive mitomycin C (MMC) in the secondary glaucoma triple procedure (SGTP) as compared to primary glaucoma triple procedure (PGTP). A prospective, controlled study that was randomized with respect to assignment to adjunctive MMC and a case-control design with respect to comparisons between SGTP and PGTP was studied. The SGTP group consisted of 49 eyes of 49 consecutive patients with primary open-angle glaucoma with a history of glaucoma filtration surgery requiring glaucoma medical therapy and in need of cataract surgery, randomized to adjunctive MMC (SGTP MMC subgroup of 21 eyes) and no adjunctive MMC (SGTP control subgroup of 28 eyes). The PGTP group consisted of 49 PGTP cases closely matched to the SGTP cases with respect to age, race, gender, MMC use, C:D ratio, and systemic diseases. Trabeculectomy combined with phacoemulsification and a small incision (5 x 6 mm), all polymethylmethacrylate posterior chamber intraocular lens implantation with or without adjunctive MMC (0.5 mg/ml for 1 minute), was performed....Continue Reading

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Citations

Dec 28, 1999·Journal of Cataract and Refractive Surgery·A CaporossiA Balestrazzi
Oct 28, 2011·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Zhong-Jie LinXiao-He Lu
Nov 16, 2001·Journal of Cataract and Refractive Surgery·R J Casson, J F Salmon
Jan 15, 2005·Current Opinion in Ophthalmology·Carlos VergesCosme Lavin
Apr 1, 2005·Acta Ophthalmologica Scandinavica·J A MaquetN Laguna
Oct 1, 2009·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Tahrwat H MokbelEhab H Nematallah
Oct 20, 2005·The Cochrane Database of Systematic Reviews·M WilkinsR Wormald
Jan 27, 2004·Current Opinion in Ophthalmology·C Vass, R Menapace
Jan 10, 2001·Current Opinion in Ophthalmology·A Storr-Paulsen, P Bernth-Petersen
Jul 1, 1999·Current Opinion in Ophthalmology·T W Samuelson
Nov 7, 2015·The Cochrane Database of Systematic Reviews·Emily CabourneJennifer R Evans
May 3, 2000·Seminars in Ophthalmology·M F Smith, J W Doyle
May 28, 2016·Journal of Current Glaucoma Practice·Raquel RodriguezJuan Francisco Batlle

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