The role of adrenaline in cardiopulmonary resuscitation

Critical Care : the Official Journal of the Critical Care Forum
Christopher J R Gough, Jerry P Nolan

Abstract

Adrenaline has been used in the treatment of cardiac arrest for many years. It increases the likelihood of return of spontaneous circulation (ROSC), but some studies have shown that it impairs cerebral microcirculatory flow. It is possible that better short-term survival comes at the cost of worse long-term outcomes. This narrative review summarises the rationale for using adrenaline, significant studies to date, and ongoing research.

References

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Citations

Aug 17, 2018·Critical Care : the Official Journal of the Critical Care Forum·R Jouffroy, B Vivien
May 19, 2019·Journal of Thrombosis and Haemostasis : JTH·Satoshi Gando, Takeshi Wada
Jul 7, 2019·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·E Ter Avest, H Lameijer
Apr 30, 2020·Current Opinion in Critical Care·Mikael F VallentinLars W Andersen
Mar 11, 2019·BMJ Case Reports·Charles W HwangTorben K Becker
Oct 1, 2020·Critical Care : the Official Journal of the Critical Care Forum·Constantine D MavroudisTodd J Kilbaugh
Jun 12, 2019·Journal of Clinical Monitoring and Computing·Dingyu TanXuezhong Yu
Mar 7, 2020·Frontiers in Pharmacology·Zoltán SzabóPéter P Nánási
Jan 18, 2020·Journal of the American College of Cardiology·Tasuku MatsuyamaTetsuhisa Kitamura
Jan 18, 2020·Journal of the American College of Cardiology·Allan de CaenIan K Maconochie
Oct 29, 2020·Current Opinion in Critical Care·Jasmeet Soar
Jul 16, 2021·The American Journal of Emergency Medicine·Ioannis PantazopoulosTheodoros Xanthos
Oct 10, 2018·ACS Applied Materials & Interfaces·Olga A SindeevaGleb B Sukhorukov

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