The role of age in post-cardiac arrest therapy in an elderly patient population

Physiology International
E KovácsE Zima

Abstract

We investigated the effect of age on post-cardiac arrest treatment outcomes in an elderly population, based on a local database and a systemic review of the literature. Data were collected retrospectively from medical charts and reports. Sixty-one comatose patients, cooled to 32-34 °C for 24 h, were categorized into three groups: younger group (≤65 years), older group (66-75 years), and very old group (>75 years). Circumstances of cardiopulmonary resuscitation (CPR), patients' characteristics, post-resuscitation treatment, hemodynamic monitoring, neurologic outcome and survival were compared across age groups. Kruskal-Wallis test, Chi-square test and binary logistic regression (BLR) were applied. In addition, a literature search of PubMed/Medline database was performed to provide a background. Age was significantly associated with having a cardiac arrest on a monitor and a history of hypertension. No association was found between age and survival or neurologic outcome. Age did not affect hemodynamic parameter changes during target temperature management (TTM), except mean arterial pressure (MAP). Need of catecholamine administration was the highest among very old patients. During the literature review, seven papers were identif...Continue Reading

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Citations

Dec 29, 2020·Current Opinion in Anaesthesiology·Sharon EinavEsther-Lee Marcus
May 1, 2021·Membranes·Viviane ZotzmannDawid L Staudacher
Nov 12, 2021·GeroScience·Andrea Ágnes MolnárBéla Merkely

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