The role of American Society of Anesthesiologists scores in predicting urothelial carcinoma of the upper urinary tract outcome after radical nephroureterectomy: results from a national multi-institutional collaborative study

BJU International
Alexis Arvin BerodFrench National Database of UUT UC

Abstract

Study Type--Prognosis (cohort) Level of Evidence 2b. What's known on the subject? and What does the study add? Upper urinary tract urothelial carcinoma (UUT-UC) is a rare disease, usually treated by nephroureterectomy, occurring in a population with a median age of 70 years and with frequent tobacco use and other comorbidities. We know that the American Society of Anesthesiologists (ASA) score has prognostic value in urological oncology but this has not been assessed in UUT-UC. Using a multi-institutional French database, we have shown that the 5-year cancer-specific survival differed significantly between ASA 1, ASA 2 and ASA 3 patients (83.8%, 76.9% and 70.6%, respectively; P = 0.01). ASA status had a significant impact on cancer-specific survival in univariate and multivariate analyses, with a threefold higher risk of mortality at 5 years for ASA 3 compared with ASA 1 patients (P = 0.04). • To evaluate the impact of American Society of Anesthesiologists (ASA) scores on the survival of patients treated with radical nephroureterectomy (RNU) for upper urinary tract urothelial carcinoma (UUT-UC). • A retrospective multi-institutional cohort study of the French collaborative national database of UUT-UC treated by RNU in 20 centre...Continue Reading

References

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Dec 25, 2007·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·Jacques IraniChristine Theodore
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Jul 14, 2010·The Journal of Urology·Vitaly MargulisUNKNOWN Upper Tract Urothelial Carcinoma Collaborative Group
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Oct 5, 2010·World Journal of Urology·Shahrokh F ShariatGiacomo Novara

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Citations

Jan 15, 2014·Nature Reviews. Nephrology·Lin LiKamyar Kalantar-Zadeh
Aug 26, 2014·Der Urologe. Ausg. A·S RauschA Stenzl
Nov 28, 2013·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·V ElaloufE Xylinas
Sep 10, 2014·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·P ColinM Rouprêt
Apr 2, 2013·European Urology·Morgan RouprêtUNKNOWN European Association of Urology
Sep 24, 2013·BJU International·Luis A KluthShahrokh F Shariat
Oct 19, 2016·American Journal of Surgery·Terence C ChuaJaswinder S Samra
Jul 10, 2019·Cancer Medicine·Sung Han KimUNKNOWN Urothelial Cancer-Advanced Research, Treatment (UCART) study group

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