PMID: 6161378Jan 1, 1980Paper

The role of antibody multivalency in immune effector processes

Progress in Clinical and Biological Research
D M SegalJ A Titus

Abstract

The preparation of covalently crosslinked oligomers of antibody molecules is described. It is shown that these oligomers can be used to study quantitatively the effects of multivalency on binding to cell surface Fc receptors. It is also shown that three effector systems differ in the ways in which they interact with multivalent immune complexes.

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