The role of anticoagulation in pylephlebitis

American Journal of Surgery
N BarilS Stain

Abstract

Pylephlebitis may complicate any intra-abdominal infection and carries a high mortality rate. Acute cases are usually anticoagulated to prevent thrombus extension and enteric ischemia; however, the role of anticoagulation has not been clearly defined. Over a 3-year period, pylephlebitis was diagnosed in 44 patients with portal vein thrombosis on computed tomography scan with fever, leukocytosis, and/or positive blood cultures. The charts were reviewed for etiology, extent of venous thrombosis, and method and results of treatment. Eighteen patients were hypercoagulable, due to clotting factor deficiencies (6), malignancy (8), or AIDS (4). Fifteen patients had mesenteric vein involvement. Thirty-two patients were not anticoagulated, and 5 died (3 with hypercoagulable states and 2 with normal clotting function). Twelve patients were anticoagulated, and none developed subsequent bowel infarction or died. Patients with pylephlebitis and a hypercoagulable state due to neoplasms or clotting factor deficiencies should be anticoagulated. Patients with normal clotting function and mesenteric vein involvement may also benefit. We believe anticoagulation in patients with thrombus isolated to the portal vein and normal clotting function may...Continue Reading

References

Nov 1, 1991·Southern Medical Journal·J J Drabick, F J Landry
Dec 1, 1990·Annals of Surgery·G D BranumW C Meyers
Oct 1, 1987·Archives of Surgery·J M HarchA J Donovan
Mar 1, 1985·Radiology·D MathieuP Grenier
Apr 1, 1985·AJR. American Journal of Roentgenology·D Van GansbekeJ Struyven
Apr 1, 1971·Annals of Surgery·C W Van WayL Rosenfeld
Sep 6, 1984·The New England Journal of Medicine·S Wessler, S N Gitel
Sep 1, 1982·Pediatric Infectious Disease·D L BartleyD Parham
Jan 1, 1994·Seminars in Thrombosis and Hemostasis·R L Bick, M Pegram
May 1, 1993·Southern Medical Journal·M J Perez-CruetG Cano

❮ Previous
Next ❯

Citations

May 19, 2009·Cardiovascular and Interventional Radiology·Conor O BogueBairbre L Connolly
Jan 18, 2006·Digestive Diseases and Sciences·Stephan M WildiBrenda J Hoffman
Jul 8, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Ryan M Thomas, Syed A Ahmad
Jun 14, 2000·Journal of Hepatology·D C Valla, B Condat
Sep 5, 2006·Nature Clinical Practice. Gastroenterology & Hepatology·Bertrand Condat, Dominique Valla
Aug 29, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·B CondatD Valla
Feb 24, 2006·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Ayman S AbdelrazeqStephen H Leveson
Jul 3, 2004·Journal of Clinical Gastroenterology·Elizabeth C VernaHoward J Worman
May 13, 2008·Journal of Clinical Gastroenterology·Ibrahim ErtuğrulNurgül Saşmaz
Aug 7, 2010·Southern Medical Journal·José AltamiranoRamón Bataller
Jan 13, 2005·Alimentary Pharmacology & Therapeutics·G J M WebsterS M Riordan
Feb 24, 2006·American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions·Julio A ChirinosDaniel M Lichtstein
Feb 25, 2005·AJR. American Journal of Roentgenology·Richa TandonJohn J Ross
Aug 6, 2008·World Journal of Gastroenterology : WJG·Yeon-Soo ChangSuk-Hwan Lee
Jan 13, 2010·World Journal of Gastroenterology : WJG·Francesca R PonzianiAntonio Gasbarrini
Mar 15, 2013·JSLS : Journal of the Society of Laparoendoscopic Surgeons·Adewale O AdisaOladejo O Lawal
Jun 27, 2014·Journal of Radiology Case Reports·Anna L FalkowskiPhilip E Tarr
May 27, 2010·Radiology·Roberto García FigueirasCarmen Villalba Martín
Feb 11, 2014·The American Journal of Medicine·Andrew GarrettRobert Measley
Aug 20, 2010·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·M-E GatibelzaG Levard
Dec 3, 2014·Clinics in Liver Disease·Syed Abdul BasitRobert Gish
Jul 15, 2015·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Asad J ChoudhryMartin D Zielinski
Jun 18, 2003·The American Journal of the Medical Sciences·Angelike P LiappisGary L Simon
Sep 22, 2009·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Massimo Primignani
May 16, 2009·The Journal of Emergency Medicine·Byung Kook Lee, Hyun Ho Ryu
Sep 18, 2015·The American Journal of Case Reports·Mohammed MuneerHassan Al-Thani
Apr 29, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Laurie D DeLeveUNKNOWN American Association for the Study Liver Diseases
Jul 14, 2012·Journal of Digestive Diseases·Tarun RustagiMridula Rai
Sep 25, 2010·American Journal of Surgery·Jennifer D ReaRichard L Jamison
Aug 1, 2006·Lancet·Spiros P DourakisAthanasios J Archimandritis
Jan 28, 2010·The American Journal of Medicine·Sameer ParikhPrashant Kapoor
Aug 15, 2009·Alimentary Pharmacology & Therapeutics·Y ChawlaR K Dhiman
Oct 13, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Aurelie PlessierUNKNOWN European Network for Vascular Disorders of the Liver (EN-Vie)
Nov 26, 2010·Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy·Masaru ShinozakiGiichiro Tsurita
Mar 25, 2015·Case Reports in Vascular Medicine·Ronny CohenPablo Loarte
May 6, 2015·Journal of Clinical and Experimental Hepatology·Yogesh K Chawla, Vijay Bodh
Dec 2, 2011·International Journal of Surgery Case Reports·Mohsen Mohamed KaramSaid Bedair
Jun 23, 2016·International Journal of Surgery Case Reports·Soniya PintoKen Richards
Jan 24, 2007·American Journal of Surgery·Sareh ParangiSusan Pories
Sep 19, 2016·La Revue de médecine interne·A BouvierO Deballon

❮ Previous
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