PMID: 3760889Sep 1, 1986Paper

The role of autonomic neuropathy in diabetic foot ulceration

Journal of Neurology, Neurosurgery, and Psychiatry
M E AhmedL P Le Quesne

Abstract

Five standard, non-invasive tests of cardiovascular, autonomic function were performed in each of four groups of 30 subjects: controls, group 1, diabetics without clinical evidence of neuropathy; group 2, diabetics with neuropathy, but without foot ulceration; group 3, diabetics with neuropathic ulceration of the foot. The results showed a significant impairment of autonomic function in diabetics without clinically demonstrable somatic neuropathy compared with controls diabetics with somatic neuropathy compared with those without diabetics with neuropathic ulceration compared with those with neuropathy without ulceration. Parasympathetic function was more seriously affected than sympathetic. In patients who had only mild sensory neuropathy on clinical assessment, those with ulcers had significantly greater impairment of autonomic neuropathy compared with those with uncomplicated neuropathy.

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Citations

May 1, 1991·Clinical and Experimental Dermatology·J P McFaddenI A O'Brien
Dec 1, 1990·Diabetic Medicine : a Journal of the British Diabetic Association·C LinigerJ P Assal
Sep 1, 1990·Diabetic Medicine : a Journal of the British Diabetic Association·R E RyderC A Hardisty
May 1, 1992·Diabetic Medicine : a Journal of the British Diabetic Association·C TsigosR J Young
Jan 1, 1989·Journal of Neurology, Neurosurgery, and Psychiatry·Z AliC J Fowler
Nov 1, 1986·Clinics in Endocrinology and Metabolism·M E Edmonds
Aug 11, 2015·The British Journal of Dermatology·R S Kirsner, A C Vivas
Apr 1, 1991·Diabetes Research and Clinical Practice·C LinigerJ P Assal
Oct 1, 1987·Acta Neurologica Scandinavica·D ClausB Neundörfer
Jul 1, 1987·Diabetic Medicine : a Journal of the British Diabetic Association·P J WatkinsM Edmonds
Jan 1, 1991·Diabetic Medicine : a Journal of the British Diabetic Association·A F MacleodP H Sonksen
Nov 30, 2000·Western Journal of Nursing Research·D K HathawayA O Gaber
Jun 27, 2020·Neuromodulation : Journal of the International Neuromodulation Society·Ashley L B RaghuJames J FitzGerald
May 19, 1988·The New England Journal of Medicine·N Parkhouse, P M Le Quesne

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