The role of avian macrophages in the production of avian lymphokines

Developmental and Comparative Immunology
P Joshi, B Glick

Abstract

Lymphocyte inhibitory factor (LyIF) and lymphocyte chemotactic factor (LCF) were produced by sensitized thymic (T) and bursal (B) cells and thymic (T) cells, respectively. The passage of sensitized T and B cells through a Sephadex G-10 column abrogated the ability of T cells to produce LyIF and LCF while B cells remained capable of producing LyIF. The return of macrophages to the adherent cell depleted population reconstituted the T cells' ability to produce LyIF and LCF. These data suggest a greater macrophage dependency of thymic cells than bursal cells in the production of lymphokines.

References

Jan 1, 1979·Scandinavian Journal of Immunology·J Hammerstrøm
Mar 1, 1987·Veterinary Immunology and Immunopathology·H Weiler, V von Bülow
Oct 4, 1969·Nature·R N MainiD C Dumonde

Citations

Feb 26, 2000·Developmental and Comparative Immunology·C Siatskas, R L Boyd
Mar 13, 2003·Pflügers Archiv : European journal of physiology·Francisco J Muñoz, Mónica Fuente
Apr 1, 1996·American Journal of Reproductive Immunology : AJRI·R Raghupathy, S Tangri

Related Concepts

Lymphocyte chemotactic factor
Sephadex G 50
Metazoa
Bursa of Fabricius
Cell Adhesion
Molecular Sieve Chromatography
Saviosol
Freund's Adjuvant
Lymphoid Cells
Lymphokines

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