The role of avian macrophages in the production of avian lymphokines

Developmental and Comparative Immunology
P Joshi, B Glick


Lymphocyte inhibitory factor (LyIF) and lymphocyte chemotactic factor (LCF) were produced by sensitized thymic (T) and bursal (B) cells and thymic (T) cells, respectively. The passage of sensitized T and B cells through a Sephadex G-10 column abrogated the ability of T cells to produce LyIF and LCF while B cells remained capable of producing LyIF. The return of macrophages to the adherent cell depleted population reconstituted the T cells' ability to produce LyIF and LCF. These data suggest a greater macrophage dependency of thymic cells than bursal cells in the production of lymphokines.


Jan 1, 1979·Scandinavian Journal of Immunology·J Hammerstrøm
Mar 1, 1987·Veterinary Immunology and Immunopathology·H Weiler, V von Bülow
Oct 4, 1969·Nature·R N MainiD C Dumonde


Feb 26, 2000·Developmental and Comparative Immunology·C Siatskas, R L Boyd
Mar 13, 2003·Pflügers Archiv : European journal of physiology·Francisco J Muñoz, Mónica Fuente
Apr 1, 1996·American Journal of Reproductive Immunology : AJRI·R Raghupathy, S Tangri

Related Concepts

Lymphocyte chemotactic factor
Sephadex G 50
Bursa of Fabricius
Cell Adhesion
Molecular Sieve Chromatography
Freund's Adjuvant
Lymphoid Cells

Related Feeds

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.