PMID: 8602127Apr 26, 1996Paper

The role of BCG vaccine in the prevention and control of tuberculosis in the United States. A joint statement by the Advisory Council for the Elimination of Tuberculosis and the Advisory Committee on Immunization Practices

MMWR. Recommendations and Reports : Morbidity and Mortality Weekly Report. Recommendations and Reports

Abstract

This report updates and replaces previous recommendations regarding the use of Bacillus of Calmette and Guerin (BCG) vaccine for controlling tuberculosis (TB) in the United States (MMWR 1988;37:663-4, 669-75). Since the previous recommendations were published, the number of TB cases have increased among adults and children, and outbreaks of multidrug-resistant TB have occurred in institutions. In addition, new information about the protective efficacy of BCG has become available. For example, two meta-analyses of the published results of BCG vaccine clinical trials and case-control studies confirmed that the protective efficacy of BCG for preventing serious forms of TB in children is high (i.e., > 80%). These analyses, however, did not clarify the protective efficacy of BCG for preventing pulmonary TB in adolescents and adults; this protective efficacy is variable and equivocal. The concern of the public health community about the resurgence and changing nature of TB in the United States prompted a re-evaluation of the role of BCG vaccination in the prevention and control of TB. This updated report is being issued by CDC, the Advisory Committee for the Elimination of Tuberculosis, and the Advisory Committee on Immunization Prac...Continue Reading

Related Concepts

Related Feeds

Antitubercular Agents (ASM)

Antitubercular agents are pharmacologic agents for treatment of tuberculosis. Discover the latest research on antitubercular agents here.

Antitubercular Agents

Antitubercular agents are pharmacologic agents for treatment of tuberculosis. Discover the latest research on antitubercular agents here.

Related Papers

MMWR. Recommendations and Reports : Morbidity and Mortality Weekly Report. Recommendations and Reports
Advisory Committee on Immunization Practices, Centers for Disease Control and Prevention (CDC)
MMWR. Recommendations and Reports : Morbidity and Mortality Weekly Report. Recommendations and Reports
Paul A JensenCDC
MMWR. Recommendations and Reports : Morbidity and Mortality Weekly Report. Recommendations and Reports
Eric E MastAdvisory Committee on Immunization Practices (ACIP) Centers for Disease Control and Prevention (CDC)
MMWR. Recommendations and Reports : Morbidity and Mortality Weekly Report. Recommendations and Reports
© 2021 Meta ULC. All rights reserved