The role of botulinum toxin a in the establishment of symmetry in pediatric paralysis of the lower lip

JAMA Facial Plastic Surgery
Siba HaykalGregory H Borschel

Abstract

Botulinum toxin A has been described as an effective adjunct treatment for achieving symmetry in adults with facial paralysis. Few investigators have described the use of botulinum toxin A in pediatric patients with facial paralysis. To present our preliminary experience with botulinum toxin A in pediatric patients presenting with asymmetry of the lower lip. We performed a retrospective medical record review of all pediatric patients (age range, 4-17 years; mean [SD] age, 11.2 [4.7] years) with facial paralysis who were treated with botulinum toxin A injections from January 1, 2004, through December 31, 2012. Patients presented for treatment at The Hospital for Sick Children, Toronto, Ontario, Canada, or the Massachusetts Eye and Ear Infirmary, Boston. Using facial analysis software, we measured lower lip asymmetry in the patients' photographs before and after treatment, at rest, and in a dynamic state. We performed analysis of variance to assess for improvement in symmetry. We identified 18 patients with the following 3 primary indications for treatment: focal lip asymmetry (n = 11), extensive hemifacial asymmetry (n = 5), and focal synkinesis (n = 2). We found no complications related to botulinum toxin A treatment. The mean ...Continue Reading

References

Apr 1, 1994·Plastic and Reconstructive Surgery·B Guyuron, S W Huddleston
Feb 1, 1996·Clinical Otolaryngology and Allied Sciences·M W ArmstrongJ A Murray
Jul 17, 1998·Journal of Neurology, Neurosurgery, and Psychiatry·B BoroojerdiJ Noth
Jan 27, 2004·Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology·Maurício de Maio
Aug 17, 2004·British Journal of Plastic Surgery·G HussainL R Tomat
Apr 30, 2005·Plastic and Reconstructive Surgery·Neil W Bulstrode, Douglas H Harrison
Jun 19, 2007·Plastic and Reconstructive Surgery·Akikazu UdagawaMasaharu Ichinose
Sep 7, 2007·Plastic and Reconstructive Surgery·Maurício de Maio, Ricardo Ferreira Bento
Dec 18, 2009·American Journal of Otolaryngology·Robin W LindsayTessa A Hadlock
May 4, 2011·Acta Oto-laryngologica·Simonetta MoniniMaurizio Barbara
Apr 10, 2012·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Julia K Terzis, Dimitrios Karypidis
Jul 13, 2012·Ophthalmic Plastic and Reconstructive Surgery·Ozlem Eşki Yücel, Nurşen Artürk
Feb 28, 2013·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Jin Kim
May 21, 2013·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Ki Hoon ChoiJin Kim

❮ Previous
Next ❯

Citations

Nov 28, 2015·Facial Plastic Surgery Clinics of North America·Omid B MehdizadehWilliam Matthew White
Jun 28, 2016·Plastic and Reconstructive Surgery·Jordan P SteinbergJoseph K Williams
Oct 19, 2016·Annales de chirurgie plastique et esthétique·P GuerreschiV Martinot-Duquennoy
Feb 27, 2019·Plastic and Reconstructive Surgery·Stav BrownShai M Rozen
Oct 22, 2015·Current Opinion in Otolaryngology & Head and Neck Surgery·Pundrique R SharmaGregory H Borschel

❮ Previous
Next ❯

Methods Mentioned

BETA
sedation

Software Mentioned

facial
MEEI
Mixed SAS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The American Journal of Hospice & Palliative Care
M Martin
European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
R LaskawiA Baetz
Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery
M AbdollahzadehJ T Rutka
© 2022 Meta ULC. All rights reserved