The role of BTA stat Test in follow-up of patients with bladder cancer: results from FinnBladder studies

World Journal of Urology
Mika-P Raitanen, FinnBladder Group

Abstract

To summarize the results of the FinnBladder studies of the BTA stat Test in follow-up of bladder cancer and more importantly to provide guidelines for daily clinical practise. Voided urine samples of 501 patients were obtained prior to cystoscopy and split for culture, cytology and BTA stat testing. The overall sensitivity and specificity for the BTA stat Test were calculated, factors interfering with testing and the role of false positive test result were evaluated. Out of 501 patients 133 (26.5%) had a bladder cancer recurrence at cystoscopy, of which BTA stat Test detected 71 (53.4%). In the remaining 368 patients, 96 (26.1%) had a positive BTA stat Test result. An additional 9 (16.4%) recurrences were detected at further examinations. The overall sensitivities and specificities for the BTA stat Test and cytology were 56.0, 19.2 and 85.7%, and 98.3%, respectively. Urine infection and past BCG instillations and present instillations of any type caused false positive test result. Out of 79 patients with positive BTA stat Test and negative cystoscopy, 6 (7.6%) had recurrence at next scheduled follow-up cystoscopy. Although BTA stat Test cannot replace cystoscopy in the follow-up of patients with bladder cancer, it could replace...Continue Reading

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Citations

Apr 9, 2010·Der Urologe. Ausg. A·P J GoebellB Wullich
Dec 7, 2007·World Journal of Urology·B J Schmitz-DrägerH B Grossman
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