The role of China in the global spread of the current cholera pandemic

PLoS Genetics
Xavier DidelotBiao Kan

Abstract

Epidemics and pandemics of cholera, a severe diarrheal disease, have occurred since the early 19th century and waves of epidemic disease continue today. Cholera epidemics are caused by individual, genetically monomorphic lineages of Vibrio cholerae: the ongoing seventh pandemic, which has spread globally since 1961, is associated with lineage L2 of biotype El Tor. Previous genomic studies of the epidemiology of the seventh pandemic identified three successive sub-lineages within L2, designated waves 1 to 3, which spread globally from the Bay of Bengal on multiple occasions. However, these studies did not include samples from China, which also experienced multiple epidemics of cholera in recent decades. We sequenced the genomes of 71 strains isolated in China between 1961 and 2010, as well as eight from other sources, and compared them with 181 published genomes. The results indicated that outbreaks in China between 1960 and 1990 were associated with wave 1 whereas later outbreaks were associated with wave 2. However, the previously defined waves overlapped temporally, and are an inadequate representation of the shape of the global genealogy. We therefore suggest replacing them by a series of tightly delineated clades. Between 1...Continue Reading

References

Sep 15, 1972·Nature·B Cvjetanovic, D Barua
Jan 1, 1997·Journal of Bacteriology·E F MaoJ H Miller
Jun 20, 2000·Antimicrobial Agents and Chemotherapy·J L Martinez, F Baquero
Dec 19, 2000·Infection and Immunity·B PicardF Taddei
May 2, 2002·Proceedings of the National Academy of Sciences of the United States of America·Anthony R RichardsonIgor Stojiljkovic
Mar 29, 2003·Journal of Molecular Evolution·Richard E LenskiMargaret A Riley
May 23, 2003·Cold Spring Harbor Symposia on Quantitative Biology·J H MillerM M Slupska
Jan 1, 1959·The American Journal of Tropical Medicine and Hygiene·S T TANAMAL
Feb 5, 2004·Genome Biology·Stefan KurtzSteven L Salzberg
May 11, 2006·PLoS Biology·Alexei J DrummondAndrew Rambaut
Jun 23, 2006·PLoS Computational Biology·Paul D WilliamsRichard A Goldstein
Dec 8, 2006·Genetics·Xavier Didelot, Daniel Falush
Jun 23, 2009·Genome Research·Martin KrzywinskiMarco A Marra
Sep 2, 2009·Proceedings of the National Academy of Sciences of the United States of America·Jongsik ChunRita R Colwell
Nov 3, 2010·Nature Genetics·Giovanna MorelliMark Achtman
Dec 15, 2010·The New England Journal of Medicine·Chen-Shan ChinMatthew K Waldor
Jan 29, 2011·Science·Nicholas J CroucherStephen D Bentley
Mar 6, 2012·Nature Methods·Ben Langmead, Steven L Salzberg
Apr 18, 2012·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·Anton BankevichPavel A Pevzner
Jun 26, 2012·Nucleic Acids Research·Andreas UntergasserSteven G Rozen
Jul 4, 2012·Lancet·Jason B HarrisStephen B Calderwood
Aug 8, 2012·Nature Reviews. Genetics·Xavier DidelotDerrick W Crook
Aug 8, 2012·Proceedings of the National Academy of Sciences of the United States of America·Michael R Weigand, George W Sundin
Dec 25, 2012·Genome Biology·Xavier DidelotRosalind M Harding
Nov 22, 2013·The New England Journal of Medicine·Hui-Ming LuoWei-Zhong Yang
Jan 10, 2014·The New England Journal of Medicine·Alison M DevaultHendrik N Poinar
Mar 29, 2014·Science·Guy J Abel, Nikola Sander

❮ Previous
Next ❯

Citations

Aug 5, 2015·Proceedings of the National Academy of Sciences of the United States of America·Ankur B DaliaAndrew Camilli
Feb 28, 2016·The Journal of Infection·Yun LuoRuiting Lan
Nov 17, 2016·Proceedings of the National Academy of Sciences of the United States of America·Dalong HuLei Wang
Jul 28, 2016·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Feng LiaoWenpeng Gu
Nov 11, 2017·Science·François-Xavier WeillNicholas R Thomson
Nov 11, 2017·Science·Daryl DommanNicholas R Thomson
Jun 27, 2018·Nature Genetics·Daryl DommanNicholas R Thomson
Aug 10, 2019·Frontiers in Public Health·Thandavarayan RamamurthyGopinath Balakrish Nair
Sep 23, 2020·International Journal of Environmental Research and Public Health·Qingyao WangYing Liu
Aug 10, 2019·Vaccine·Jacqueline DeenJohn D Clemens
Oct 24, 2020·Nature Communications·Mihaela OpreaFrançois-Xavier Weill
Jan 23, 2021·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Murari BhandariFlavia Huygens
Feb 15, 2021·Economics and Human Biology·Kota Ogasawara, Tatsuki Inoue
Nov 25, 2021·Journal of Medical Microbiology·Mark Philip BugayongMakoto Ohnishi

❮ Previous
Next ❯

Software Mentioned

Circos
ClonalFrame
MuMMER
Primer3
PhyML
Bowtie
SPAdes

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.