The Role of Cleaning Products in Epidemic Allergic Contact Dermatitis to Methylchloroisothiazolinone/Methylisothiazolinone

Dermatitis : Contact, Atopic, Occupational, Drug
Gabriel Marrero-AlemánLeopoldo Borrego

Abstract

Sensitivity to methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI) has increased rapidly over recent years. This increase is mainly related to the extensive use of high concentrations of MI in cosmetic products, although a growing number of cases of occupational allergic contact dermatitis are caused by MCI/MI. The aim of this study was to examine the association between the increase in MCI/MI sensitization and the work performed by the patients in our area. A retrospective study was undertaken of the records of a total of 1179 patients who had undergone contact skin patch tests for MCI/MI from January 2005 to December 2015. A multivariate logistic regression analysis was performed to identify the factors independently associated with sensitivity to MCI/MI. A constant increase in MCI/MI sensitization was observed over the observation period. The only work associated with a significant increase in the prevalence of MCI/MI sensitization was cleaning, with 38.5% of the cleaning professionals with MCI/MI sensitization consulting for cosmetics-related dermatitis. Occupational sensitization to MCI/MI in cleaning professionals is worryingly increasing. This, in turn, could possibly account for many cases of cosmetics-associat...Continue Reading

References

Aug 11, 2015·Contact Dermatitis·Olivier AertsSandra Apers
Jan 13, 2016·Dermatitis : Contact, Atopic, Occupational, Drug·Andrew Scheman, David Severson
Nov 20, 2016·Contact Dermatitis·Elena Garcia-HidalgoKonrad Hungerbühler
Feb 9, 2017·European Journal of Dermatology : EJD·Olivier AertsJean-Pierre Lepoittevin

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Citations

Nov 15, 2018·Contact Dermatitis·Thanisorn SukakulWaranya Boonchai
Aug 23, 2019·Dermatitis : Contact, Atopic, Occupational, Drug·Jamie P Schlarbaum, Erin M Warshaw
Feb 13, 2020·Dermatitis : Contact, Atopic, Occupational, Drug·Lauren Claire HollinsAlexandra Flamm
Apr 5, 2020·International Journal of Environmental Research and Public Health·Wolfgang UterIan R White
Mar 30, 2021·Current Allergy and Asthma Reports·Erica B LeeAshley Wysong

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