PMID: 11913918Mar 27, 2002Paper

The role of corticosteroids in the management of childhood asthma

The Medical Journal of Australia
P van Asperen PeterThoracic Society of Australia and New Zealand

Abstract

Preventive treatment: * Inhaled corticosteroids are indicated in children with asthma who have more than mild persistent asthma or are unresponsive to non-steroidal medications after 2-4 weeks. * Initial administration of 400 microg/day of chlorofluorocarbon-beclomethasone dipropionate, or budesonide, or 200 microg/day of fluticasone propionate or hydrofluoroalkane-beclomethasone dipropionate, is suggested, with subsequent titration of the dose to achieve ongoing control with the lowest dose possible. * In situations where asthma control cannot be achieved with the above doses of inhaled corticosteroids, the addition of a long-acting beta2-agonist, theophylline or a leukotriene antagonist should be considered. * Specialist referral is recommended in children requiring high doses of inhaled steroids, regular oral steroids or in whom there is concern about possible steroid side effects. Treatment of acute asthma: * Systemic corticosteroid therapy is recommended for children with moderate to severe acute asthma or if there is incomplete response to beta2-agonists. * Initial administration of 1 mg/kg prednisolone (maximum, 50 mg) orally is suggested, and this may be repeated every 12-24 hours, depending on response. While a course ...Continue Reading

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Citations

Sep 5, 2006·The Medical Journal of Australia·Patrick Patradoon-HoGeoffrey R Ambler
Apr 19, 2006·The Medical Journal of Australia·Anne B ChangUNKNOWN Thoracic Society of Australia and New Zealand
Apr 16, 2010·The Cochrane Database of Systematic Reviews·Francine M DucharmeToby J Lasserson

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