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The role of cyclic AMP in the positive inotropic effect mediated by beta 1- and beta 2-adrenoceptors in isolated human right atrium

Naunyn-Schmiedeberg's Archives of Pharmacology

May 1, 1987

K IkezonoO E Brodde

Abstract

The time course of the effects of isoprenaline (3 X 10(-7) mol/l) on contractile force and on the cyclic AMP level was studied in the electrically driven isolated muscle strip of the human right atrium. Isoprenaline produced a rise in cyclic AMP content (maximum increase after 60 s) pre...read more

Mentioned in this Paper

Myocardial Contraction
Myocardium
Pavatym
Propanolamines
Beta-adrenergic receptor
Rexigen
In Vitro [Publication Type]
Novodrin
Bisoprolol, Fumarate (2: 1) Salt
Cyclic AMP, (R)-Isomer
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The role of cyclic AMP in the positive inotropic effect mediated by beta 1- and beta 2-adrenoceptors in isolated human right atrium

Naunyn-Schmiedeberg's Archives of Pharmacology

May 1, 1987

K IkezonoO E Brodde

PMID: 2886923

DOI: 10.1007/bf00169125

Abstract

The time course of the effects of isoprenaline (3 X 10(-7) mol/l) on contractile force and on the cyclic AMP level was studied in the electrically driven isolated muscle strip of the human right atrium. Isoprenaline produced a rise in cyclic AMP content (maximum increase after 60 s) pre...read more

Mentioned in this Paper

Myocardial Contraction
Myocardium
Pavatym
Propanolamines
Beta-adrenergic receptor
Rexigen
In Vitro [Publication Type]
Novodrin
Bisoprolol, Fumarate (2: 1) Salt
Cyclic AMP, (R)-Isomer

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123
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