The role of cystoscopy in the diagnosis of Hunner's ulcer disease
Abstract
Interstitial cystitis can be classified into Hunner's ulcer and nonulcer disease, which are easily distinguished by cystoscopic examination. Although therapeutic options may differ between these 2 groups, the diagnosis of interstitial cystitis is currently established by many clinicians in the absence of cystoscopy. We determined whether clinical parameters alone without cystoscopic evaluation could reliably distinguish the patient with Hunner's ulcer vs nonHunner's ulcer disease. Data were collected on 184 women and 39 men who met National Institute of Diabetes, Digestive and Kidney Diseases criteria for interstitial cystitis and who were evaluated at our institution between 1990 and 2005. A total of 86 patients with Hunner's ulcer were consecutively identified. Of patients with nonHunner's ulcer disease seen during that period a cohort of 137 who were consecutively identified were selected as a comparison group. Clinical data on each patient were collected. The groups were compared by the 2-sample t test, the Mann-Whitney test when appropriate and the chi-square test. No significant differences in clinical parameters were found between women and men in either group. The female-to-male ratio was 6:1 and 3:1 in the nonHunner's ...Continue Reading
References
APF, HB-EGF, and EGF biomarkers in patients with ulcerative vs. non-ulcerative interstitial cystitis
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