The role of default mode network in semantic cue integration.

NeuroImage
Lucilla LanzoniElizabeth Jefferies

Abstract

Recent accounts of large-scale cortical organisation suggest that the default mode network (DMN) is positioned at the top of a principal gradient, reflecting the separation between heteromodal and unimodal sensory-motor regions in patterns of connectivity and in geodesic distance along the cortical surface (Margulies et al., 2016). This isolation of DMN from external inputs might allow the integration of disparate sources of information that can constrain subsequent cognition. We tested this hypothesis by manipulating the degree to which semantic decisions for ambiguous words (e.g. jam) were constrained by preceding visual cues depicting relevant spatial contexts (e.g. supermarket or road) and/or facial emotions (e.g. happy vs. frustrated). We contrasted (i) the effects of a single preceding cue with a no-cue condition employing scrambled images, and (ii) convergent spatial and emotion cues with single cues. Single cues elicited stronger activation in the multiple demand network relative to no cues, consistent with the requirement to maintain information in working memory. The availability of two convergent cues elicited stronger activation within DMN regions (bilateral angular gyrus, middle temporal gyrus, medial prefrontal co...Continue Reading

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Citations

Jun 6, 2021·NeuroImage·Zhiyao GaoElizabeth Jefferies
Jul 1, 2021·Network Neuroscience·Giulia LioiNicolas Farrugia
Jul 7, 2021·Nature Reviews. Neuroscience·Jonathan SmallwoodDaniel S Margulies
Mar 18, 2021·Brain : a Journal of Neurology·Qiongling LiBoris C Bernhardt
Oct 9, 2021·Neuropsychologia·Nicholas E SouterElizabeth Jefferies

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Software Mentioned

FEAT ( FMRI Expert Analysis Tool )
Neurosynth
FLAME ( FMRIB s Local Analysis of Mixed Effects )
BrainNet Viewer
SHINE
FSL
BET
CONN
FLAME ( FMRIB Local Analysis of Mixed Effects )
Matlab

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