The role of depression pharmacogenetic decision support tools in shared decision making

Journal of Neural Transmission
Katarina ArandjelovicChad Bousman

Abstract

Patients discontinue antidepressant medications due to lack of knowledge, unrealistic expectations, and/or unacceptable side effects. Shared decision making (SDM) invites patients to play an active role in their treatment and may indirectly improve outcomes through enhanced engagement in care, adherence to treatment, and positive expectancy of medication outcomes. We believe decisional aids, such as pharmacogenetic decision support tools (PDSTs), facilitate SDM in the clinical setting. PDSTs may likewise predict drug tolerance and efficacy, and therefore adherence and effectiveness on an individual-patient level. There are several important ethical considerations to be navigated when integrating PDSTs into clinical practice. The field requires greater empirical research to demonstrate clinical utility, and the mechanisms thereof, as well as exploration of the ethical use of these technologies.

References

Jun 24, 2004·The Australian and New Zealand Journal of Psychiatry·Peter McManusJohn Dudley
Mar 31, 2005·The Journal of the American Board of Family Practice·W David RobinsonRachel Barnacle
Jan 24, 2006·Patient Education and Counseling·Barbara C Schouten, Ludwien Meeuwesen
Mar 2, 2006·BMC Health Services Research·Ami SchattnerNavah Jellin
May 26, 2007·Health Expectations : an International Journal of Public Participation in Health Care and Health Policy·Margaret Holmes-Rovner
Apr 25, 2008·International Journal of Medical Informatics·Marc LemireCharmian Harvey
Dec 1, 2009·International Journal of Geriatric Psychiatry·Patrick J RaueMartha L Bruce
Dec 31, 2009·Human Psychopharmacology·Lesley BerkMichael Berk
Mar 12, 2010·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Jo Anne SireyHelen C Kales
Nov 29, 2011·Journal of Psychiatric Research·Boadie W DunlopHelen S Mayberg
Oct 11, 2012·Translational Psychiatry·D K Hall-FlavinD A Mrazek
Oct 25, 2012·The Australian and New Zealand Journal of Psychiatry·João Data-Franco, Michael Berk
Jan 30, 2013·Clinical Therapeutics·Jo Anne SireyMartha L Bruce
Mar 13, 2014·Journal of the American Board of Family Medicine : JABFM·Leif I SolbergArne Beck
Jun 28, 2014·Journal of Affective Disorders·Rosa A van GriekenAart H Schene
Jul 18, 2014·Psychological Medicine·L TecutaG A Fava
Jul 20, 2014·Clinics in Geriatric Medicine·Benoit H MulsantMark J Rapoport
Sep 16, 2014·Journal of Mental Health·Alyssa C Milton, Barbara A Mullan
Aug 6, 2015·Clinical Psychopharmacology and Neuroscience : the Official Scientific Journal of the Korean College of Neuropsychopharmacology·Ajeet B Singh
Aug 25, 2015·Psychiatry Research·Lucas M WaldenDaniel J Müller
Sep 29, 2015·JAMA Internal Medicine·Annie LeBlancVictor M Montori
May 3, 2016·The Lancet. Psychiatry·Chad A Bousman, Malcolm Hopwood
Jul 20, 2016·Patient Education and Counseling·Judith H Hibbard
Jul 28, 2016·Patient Education and Counseling·Sarah T Hawley, Arden M Morris
Mar 16, 2017·Health Expectations : an International Journal of Public Participation in Health Care and Health Policy·Lilisbeth Perestelo-PerezPedro Serrano-Aguilar
May 13, 2017·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Mike Slade
May 13, 2017·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Winfried Rief, Julia Anna Glombiewski
Oct 4, 2017·JAMA Psychiatry·Jo Anne SireyHelen C Kales
Oct 12, 2017·Australasian Psychiatry : Bulletin of Royal Australian and New Zealand College of Psychiatrists·Victoria Alguera-LaraDavid Castle

❮ Previous
Next ❯

Citations

Feb 18, 2020·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Abdullah Al MarufChad A Bousman
Sep 15, 2020·Journal of American College Health : J of ACH·Jenny RogojanskiUNKNOWN and Mobilizing Minds Research Group
May 20, 2020·Pharmacogenomics and Personalized Medicine·Mirko ManchiaBernardo Carpiniello
Apr 8, 2018·Journal of Neural Transmission·Hilario Blasco-Fontecilla
Mar 7, 2021·Journal of Personalized Medicine·Angelos HalarisElizabeth A Whitham
Apr 1, 2021·British Journal of Pharmacology·Malgorzata BorczykMichal Korostynski
Nov 17, 2021·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Chad A BousmanRoger E Thomas

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Health Expectations : an International Journal of Public Participation in Health Care and Health Policy
Paul C SchroyPeter Davidson
Journal of the American Board of Family Medicine : JABFM
Leif I SolbergArne Beck
© 2022 Meta ULC. All rights reserved